Results 141 to 150 of about 224,774 (318)

One-pot Enzymatic Synthesis of Deoxy-thymidine-diphosphate (TDP)-2-deoxy-∝-d-glucose Using Phosphomannomutase

open access: yes, 2010
Production of deoxy-thymidine-diphosphate (TDP)-sugars as substrates of glycosyltransferases, has been one of main hurdles for combinatorial antibiotic biosynthesis, which combines sugar moiety with aglycon of various antibiotics. Here, we report the one-
Kang, Young Bok (Abraham)   +10 more
core  

Oxidation of glucose by iodine in the presence of insulin [PDF]

open access: yes, 1923
This investigation was undertaken with the purpose of determining whether insulin, alone or in the presence of certain animal fluids, has any influence upon glucose in vitro. The establishment of such an influence might have much significance in relation
Alles, Gordon A., Winegarden, Howard M.
core  

Association between prediagnostic serum metabolites and pancreatic ductal adenocarcinoma risk in two prospective cohorts

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Exposures and mechanisms that contribute to and promote pancreatic ductal adenocarcinoma (PDAC) remain unclear. In this study, the authors applied metabolomics to better understand PDAC etiology by examining associations between prediagnostic serum metabolites and PDAC risk.
Ting Zhang   +7 more
wiley   +1 more source

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

open access: yesiMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu   +8 more
wiley   +1 more source

Characterization of Newly Discovered Polyester Polyurethane‐Degrading Methylobacterium aquaticum Strain A1

open access: yesJournal of Basic Microbiology, EarlyView.
ABSTRACT In this study, we present Methylobacterium aquaticum A1, a novel strain capable of degrading polyester polyurethane (PE‐PUR). The attachment of M. aquaticum A1 to PE‐PUR and its degradation capabilities were verified using Scanning Electron Microscopy (SEM) and Fourier‐Transform Infrared Spectroscopy (FT‐IR).
Seong Hyeon Lee   +4 more
wiley   +1 more source

Synthesis of \u3cem\u3eN\u3c/em\u3e-Acetyl-ᴅ-quinovosamine in \u3cem\u3eRhizobium etli\u3c/em\u3e CE3 is Completed After Its 4-keto-precursor is Linked to a Carrier Lipid [PDF]

open access: yes, 2017
Bacterial O-antigens are synthesized on lipid carriers before being transferred to lipopolysaccharide core structures. Rhizobium etli CE3 lipopolysaccharide is a model for understanding O-antigen biological function.
Li, Tiezheng, Noel, K. Dale
core   +1 more source

Fabrication of Lithium/Strontium‐Releasing Smart Bioactive Glasses with Anti‐Inflammatory and Osteogenic Effects Tailored to Pathological Stages

open access: yesMacromolecular Bioscience, EarlyView.
Bioactive glasses with controllable dual ion release capability are developed to aid bone regeneration. The bioactive glasses rapidly release lithium ions that exert an anti‐inflammatory effect, suppressing inflammation after bone injury. Simultaneously, the bioactive glasses slowly release strontium ions, which support bone formation by suppressing ...
Hirohiko Sakai   +6 more
wiley   +1 more source

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