Mannose 6-phosphate receptor-mediated endocytosis of acid hydrolases: internalization of beta-glucuronidase is accompanied by a limited dephosphorylation. [PDF]
, 1986 Christopher A. Gabel, S A Foster
openalex +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Epilepsia Open, EarlyView.Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
LYSET/TMEM251- a novel key component of the mannose 6-phosphate pathway. [PDF]
Autophagy, 2023 Qiao W, Richards CM, Jabs S.
europepmc +1 more source
Exploration, EarlyView.In this study, Zhang and colleagues show that drinking‐water supplementation of D‐mannose serves as an effective and potential therapeutic of type 2 diabetes, with improvement of both liver health and bone mass. The effect is exerted through suppressing macrophage release of extracellular vesicles based on metabolic control of CD36 expression.
Sha Zhang +21 more
wiley +1 more source
Structures of the mannose-6-phosphate pathway enzyme, GlcNAc-1-phosphotransferase. [PDF]
Proc Natl Acad Sci U S A, 2022 Gorelik A, Illes K, Bui KH, Nagar B.
europepmc +1 more source
Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality. [PDF]
, 1994 M. Lau +5 more
openalex +1 more source
Food Biomacromolecules, EarlyView.Abstract Metabolic syndrome (MetS) is a complex noncommunicable condition characterized by central obesity, insulin resistance, hyperlipidemia, hypertension, and hyperglycemia. Epidemiological evidence shows that MetS affects a third of the global population; however, due to its complex pathogenesis and limited drug therapy options, the increasing ...
Josiah Owuor Oyalo +3 more
wiley +1 more source
LYSET/TMEM251/GCAF is critical for autophagy and lysosomal function by regulating the mannose-6-phosphate (M6P) pathway. [PDF]
Autophagy, 2023 Zhang B, Yang X, Li M.
europepmc +1 more source
Granzymes A and B are targeted to the lytic granules of lymphocytes by the mannose-6-phosphate receptor. [PDF]
, 1993 Gillian M. Griffiths, S Isaaz
openalex +1 more source
Future Postharvest and Food, EarlyView.Characterization of dairy–cereal grain‐based probiotic beverage (Raabadi) powder. ABSTRACT There is gaining interest in innovative instant probiotic food powders with the benefits of dairy and plant food matrices to meet the growing demand for sustainable and healthy probiotic food options.
Kamalesh Kumar Meena +5 more
wiley +1 more source