Results 161 to 170 of about 224,774 (318)

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

Small, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai, Dhwani Rana, Mitali Patel, Neha Bajwa, Rajendra Prasad, Lalitkumar K. Vora   +5 more
wiley   +1 more source

A Bacterial Pathogen Senses Host Mannose to Coordinate Virulence

iScience, 2019
Summary: Bacterial pathogens are thought to activate expression of virulence genes upon detection of host-associated cues, but identification of the nature of such signals has proved difficult.
Lifan Wei, Haoxian Qiao, Brandon Sit, Kaiyu Yin, Guanhua Yang, Ruiqing Ma, Jiabao Ma, Chun Yang, Jun Yao, Yue Ma, Jingfan Xiao, Xiaohong Liu, Yuanxing Zhang, Matthew K. Waldor, Qiyao Wang   +14 more
doaj  

Tail-specific antibodies that block return of 46,000 M(r) mannose 6-phosphate receptor to the trans-Golgi network [PDF]

, 1993
Christine Schulze-Garg, Christian Böker, S.K. Nadimpalli, Kurt Von Figura, Annette Hille‐Rehfeld   +4 more
openalex   +1 more source

Nanomedicine for Oral Delivery: Strategies to Overcome the Biological Barriers

Small Methods, EarlyView.
Oral delivery is a preferred administration route for many clinical applications, valued for its strong patient compliance. In this review, how nanoparticles are engineered and deployed to overcome the gastrointestinal barriers that impede clinical translation of oral delivery formulations is examined.
Luke J. Kubiatowicz, Nima Pourafzal, Audrey T. Zhu, Zhongyuan Guo, Ronnie H. Fang, Liangfang Zhang   +5 more
wiley   +1 more source

Downregulation of Mannose-6-Phosphate Receptors in Fabry Disease Cardiomyopathy: A Potential Target for Enzyme Therapy Enhancement. [PDF]

J Clin Med, 2022
Frustaci A, Verardo R, Scialla R, Bagnato G, Verardo M, Alfarano M, Russo MA.   +6 more
europepmc   +1 more source

Changes in Insulin-Like Growth Factor-II/Mannose-6-Phosphate Receptor during Growth and Atresia of Ovine Ovarian Follicles [PDF]

, 1994
M.P. Teissier, Philippe Monget, Danielle Monniaux, Philippe Durand   +3 more
openalex   +1 more source

The Biomaterial and Blood Clot Complex: A Crucial Early Environment for Osteo‐Coagulo‐Immunomodulation and the Advancement of Bone Biomaterials

Small Structures, EarlyView.
Various properties of bone biomaterials can modulate components of the blood clot (including the fibrin network, red blood cells, platelets, and the complement system) in vivo implantation, leading to the formation of a biomaterial–blood clot complex (BBCC) significantly impacting subsequent osteoimmunomodulation.
Zongpu Han, Jieyun Xu, Xinyu Guo, Lingyu Liang, Linjun Zhang, Yu Su, Wendong Gao, Qingming Tang, Lili Chen, Zhuofan Chen, Yin Xiao, Zetao Chen   +11 more
wiley   +1 more source

Identification and structural characterisation of a partially arabinosylated lipoarabinomannan variant isolated from a Corynebacterium glutamicum ubiAmutant [PDF]

, 2007
Arabinan polysaccharide side-chains are present in both Mycobacterium tuberculosis and Corynebacterium glutamicum in the heteropolysaccharide arabinogalactan (AG), and in M. tuberculosis in the lipoglycan, lipoarabinomannan (LAM).
Alderwick, Luke J., Besra, Gurdyal S, Dell, Anne, Eggeling, Lothar, Gilleron, Martine, Giordano, Assunta, Hitchen, Paul, Krumbach, Karin, Mishra, Arun K., Morris, Howard R., Nigou, Jerome, Tatituri, Raju Venkata Veera   +11 more
core  

The overexpressed human 46-kDa mannose 6-phosphate receptor mediates endocytosis and sorting of beta-glucuronidase. [PDF]

, 1990
Hiroshi Watanabe, Jeffrey H. Grubb, William S. Sly   +2 more
openalex   +1 more source

A paper‐based bi‐enzymatic sensor for chemiresistive glucose detection

VIEW, EarlyView.
This paper presents the development of a paper‐based glucose sensor utilizing poly(3,4‐ethylene‐dioxythiophene) polystyrene sulfonate (PEDOT:PSS) and a bi‐enzymatic system with Horseradish Peroxidase (HRP) and Glucose Oxidase (GOx). The chemiresistive sensor is optimized for detecting glucose in biofluids such as saliva, requiring only 40 µL of sample ...
Riccardo Zulli, Jacopo Giaretta, Theja Prabhakar, Ronil J Rath, Suvan Shrestha, Sara Spilimbergo, Syamak Farajikhah, Fariba Dehghani   +7 more
wiley   +1 more source