Results 201 to 210 of about 224,774 (318)

Chlamydia trachomatis CT229 Subverts Rab GTPase-Dependent CCV Trafficking Pathways to Promote Chlamydial Infection

open access: yesCell Reports, 2019
Summary: Chlamydial infection requires the formation of a membrane-bound vacuole, termed the inclusion, that undergoes extensive interactions with select host organelles.
Robert Faris   +5 more
doaj  

Weight Loss‐Associated Remodeling of Adipose Tissue Immunometabolism

open access: yesObesity Reviews, EarlyView.
ABSTRACT Obesity is a multifactorial condition characterized by excessive adiposity and systemic chronic low‐grade inflammation. Recent literature reflects a growing appreciation for the complex interplay between metabolism and the immune system in the pathogenesis of obesity‐related health conditions.
Paulo José Basso   +5 more
wiley   +1 more source

Genome-wide RNAi Screen Reveals a Role for Multipass Membrane Proteins in Endosome-to-Golgi Retrieval

open access: yesCell Reports, 2014
Summary: Endosome-to-Golgi retrieval is an essential membrane trafficking pathway required for many important physiological processes and linked to neurodegenerative disease and infection by bacterial and viral pathogens.
Sophia Y. Breusegem   +1 more
doaj  

Highly efficient transgene‐free ErCas12a RNP‐protoplast genome editing and single‐cell regeneration in Nicotiana benthamiana for glyco‐engineering

open access: yesPlant Biotechnology Journal, EarlyView.
Summary Nicotiana benthamiana serves as a unique platform for biopharmaceutical production, offering advantages such as efficient and scalable protein synthesis. In addition, custom N‐glycans can be engineered on biopharmaceutical glycoproteins. Yet, plant‐native glycosyltransferases and glycoside hydrolases need to be removed to prevent undesired ...
Lukas C. Blumberg   +8 more
wiley   +1 more source

Mannose 6‐phosphate‐independent Lysosomal Sorting of LIMP‐2

open access: yesTraffic : the International Journal of Intracellular Transport, 2015
Judith Blanz   +6 more
semanticscholar   +1 more source

MsAREB1 enhances combined cold and saline–alkali stress tolerance by promoting ascorbic acid biosynthesis in alfalfa

open access: yesPlant Biotechnology Journal, EarlyView.
Summary Cold and saline–alkali stress are typical abiotic stresses on forage in middle and high latitudes, and they frequently occur simultaneously, decreasing the yield and quality of forage. Ascorbic acid plays an essential role in reactive oxygen species metabolism in response to abiotic stress.
Weileng Guo   +6 more
wiley   +1 more source

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