Results 211 to 220 of about 224,774 (318)

A Role for the Plastidial GPT2 Translocator in the Modulation of Lignin Biosynthesis

Plant, Cell &Environment, EarlyView.
ABSTRACT Engineering plants with reduced lignin content can result in pleiotropic growth defects. In stems of Arabidopsis plants with reduced expression of hydroxycinnamoyl CoA: shikimate hydroxycinnamoyl transferase (HCT), the plastidial glucose 6‐phosphate: phosphate co‐transporter GPT2 is highly overexpressed, and this coincides with reduced lignin ...
Aditi Subramani Raju, Abira Sahu, Chunliu Zhuo, Wayne K. Versaw, Richard A. Dixon   +4 more
wiley   +1 more source

New players and targets in mannose 6-phosphate-dependent lysosomal sorting. [PDF]

EMBO J
Zubkov N, Munro S.
europepmc   +1 more source

Functional role of cation-independent mannose 6-phosphate/insulin-like growth factor II receptor in cell adhesion and proliferation of a human myeloma cell line OPM-2 [PDF]

, 1996
Tetsuo Nishiura, Takahiro Karasuno, Hitoshi Yoshida, Hirohisa Nakao, Megumu Ogawa, Yukio Horikawa, Michihiro Yoshimura, Yu Okajima, Yuzuru Kanakura, Yoshio Kanayama, Yūji Matsuzawa   +10 more
openalex   +1 more source

Transcript correlation analysis for the identification of novel plant genes involved in iron metabolism and beyond: what next?

Plant Biology, EarlyView.
Transcript correlation analysis allowed the identification of several key nodes in the complex regulatory network of plant iron metabolism. Abstract Arabidopsis thaliana was the first plant genome to be fully sequenced, almost a quarter of a century ago, thanks to The Arabidopsis Genome Initiative, with contributions from scientists worldwide.
I. Murgia, P. Morandini
wiley   +1 more source

Isolation and characterization of the two glycosylation isoforms of low molecular weight mannose 6-phosphate receptor from bovine testis. Effect of carbohydrate components on ligand binding.

, 1991
M.M. Li, George W. Jourdian
openalex   +1 more source

The Rate of Internalization of the Mannose 6-Phosphate/Insulin-like Growth Factor II Receptor Is Enhanced by Multivalent Ligand Binding [PDF]

, 1999
Sally J. York, Lynne S. Arneson, Walter Gregory, Nancy Dahms, Stuart Kornfeld   +4 more
openalex   +1 more source

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

Advanced Healthcare Materials, Volume 14, Issue 17, July 4, 2025.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray, Shehzahdi S. Moonshi, Hang Thu Ta   +2 more
wiley   +1 more source

Low density lipoprotein receptor and cation-independent mannose 6-phosphate receptor are transported from the cell surface to the Golgi apparatus at equal rates in PC12 cells

, 1992
SA Green, R B Kelly
openalex   +1 more source

Re-expression of the Mannose 6-Phosphate Receptors in Receptor-deficient Fibroblasts [PDF]

, 1996
Hélène Munier‐Lehmann, Fabienne Mauxion, Ulrike Bauer, Peter Lobel, Bernard Hoflack   +4 more
openalex   +1 more source

Sortilin‐Mediated Rapid, Precise and Sustained Degradation of Membrane Proteins via mRNA‐Encoded Lysosome‐Targeting Chimera

Advanced Science, Volume 12, Issue 25, July 3, 2025.
The study identified sortilin as a promising LTR, enabling targeted degradation of oncogenic proteins through an mRNA‐encoded MedTAC strategy. In a mouse model, MedTACPTK7 reduced PTK7 by up to 80%, extended survival, and showed excellent pharmacokinetics without toxicity, providing a scalable platform for targeted therapies.
Xin Chang, Xinyu Qiu, Xiaoning Tong, Shaoju Gan, Weicheng Yi, Sitao Xie, Xiangsheng Liu, Chao Zuo, Weihong Tan   +8 more
wiley   +1 more source