Structure analysis of biologically important prokaryotic glycopolymers [PDF]
Of the many post-translational modifications organisms can undertake, glycosylation is the most prevalent and the most diverse. The research in this thesis focuses on the structural characterisation of glycosylation in two classes of glycopolymer (
Ventura, Valeria Victoria+1 more
core +1 more source
The emerging field of MXene/MBene materials has progressed rapidly, advancing diverse research fields, including biomedical engineering, biomedicine, agriculture, and the environment. This nanobiotechnology can tackle longstanding challenges in these areas.
Alireza Rafieerad, Ahmad Amiri
wiley +1 more source
Unveiling the metabolic fate of monosaccharides in cell membranes with glycomic and glycoproteomic analyses. [PDF]
Cell membrane protein glycosylation is dependent on the metabolic state of the cell as well as exogenous nutrients available. Although the metabolism and interconversion of monosaccharides have been well-studied, their incorporation into cell surface ...
Cheng, Zhi+5 more
core
Designing the Next Generation of Biomaterials through Nanoengineering
Nanoengineering enables precise control over biomaterial interactions with living systems by tuning surface energy, defects, porosity, and crystallinity. This review highlights how these nanoscale design parameters drive advances in regenerative medicine, drug delivery, bioprinting, biosensing, and bioimaging, while outlining key translational ...
Ryan Davis Jr.+3 more
wiley +1 more source
Optimisation of the enzyme-linked lectin assay for enhanced glycoprotein and glycoconjugate analysis [PDF]
Lectin’s are proteins capable of recognising and binding to specific oligosaccharide tructures found on glycoproteins and other biomoloecules. As such they have found tility for glycoanalytical applications.
Afrough+48 more
core +2 more sources
Advances and Strategies in Enhancing mRNA Cancer Vaccines
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang+4 more
wiley +1 more source
Identification and structural characterisation of a partially arabinosylated lipoarabinomannan variant isolated from a Corynebacterium glutamicum ubiAmutant [PDF]
Arabinan polysaccharide side-chains are present in both Mycobacterium tuberculosis and Corynebacterium glutamicum in the heteropolysaccharide arabinogalactan (AG), and in M. tuberculosis in the lipoglycan, lipoarabinomannan (LAM).
Alderwick, Luke J.+11 more
core
Transient Expression of Tetrameric Recombinant Human Butyrylcholinesterase in Nicotiana benthamiana. [PDF]
To optimize the expression, extraction and purification of plant-derived tetrameric recombinant human butyrylcholinesterase (prBChE), we describe the development and use of plant viral amplicon-based gene expression system; Tobacco Mosaic Virus (TMV) RNA-
Alkanaimsh, Salem+13 more
core +1 more source
Metabolic glycoengineering combined with click chemistry efficiently immobilizes clickable factor H (FH)‐binding peptides onto endothelial cell surfaces, creating stable, uniform coatings that recruit FH and enhance resistance to complement‐mediated inflammation.
Jannes Felsch+7 more
wiley +1 more source
Differences in the endosomal distributions of the two mannose 6-phosphate receptors. [PDF]
Multiple immunolabeling of cryosections was performed to compare the subcellular distributions of the two mannose 6-phosphate receptors (MPRs) involved in the intracellular targeting of lysosomal enzymes: the cation-dependent (CD) and cation-independent (CI) MPR.
Klumperman, J.+6 more
openaire +5 more sources