Results 91 to 100 of about 65,862 (234)

Role of N-glycosylation in oral cancer [PDF]

open access: yes, 2017
Oral squamous cell carcinoma represents more than 90% head and neck cancers with high incidence rate and morbidity. To date, little is known about the molecular mechanisms responsible for OSCC initiation and progression to advanced disease.
Bukhari, Samah
core  

Rhabdomyosarcoma targeting with tuned porous silicon nanoparticles

open access: yesNano Select
We describe porous silicon nanoparticles (pSiNP) chemically functionalized with an analog of mannose 6‐phosphate (AMFA) and a porphyrin derivative to target aggressive pediatric Rhabdomyosarcoma (RMS) tumor cells.
Sofia Dominguez‐Gil   +10 more
doaj   +1 more source

The GARP Complex Is Involved in Intracellular Cholesterol Transport via Targeting NPC2 to Lysosomes

open access: yesCell Reports, 2017
Proper intracellular cholesterol trafficking is critical for cellular function. Two lysosome-resident proteins, NPC1 and NPC2, mediate the egress of low-density lipoprotein-derived cholesterol from lysosomes.
Jian Wei   +10 more
doaj   +1 more source

Herpes simplex virus glycoprotein D acquires mannose 6-phosphate residues and binds to mannose 6-phosphate receptors.

open access: yesJournal of Biological Chemistry, 1994
Herpes simplex viruses (HSV) use multiple and sequential receptors to enter host cells. HSV glycoprotein D (gD) has been implicated in binding to cellular receptors that facilitate virus penetration into cells. We used soluble forms of gD that were expressed in Chinese hamster ovary cells to characterize and identify a putative cellular receptor for ...
Kevin S. Dingwell   +6 more
openaire   +3 more sources

Glycosidases Interact Selectively With Mannose‐6‐Phosphate Receptors of Bull Spermatozoa

open access: yesJournal of Cellular Biochemistry, 2016
ABSTRACTGlycosidases may play a role in sperm maturation during epididymal transit. In this work, we describe the interaction of these enzymes with bull spermatozoa. We found that β‐galactosidase associated to spermatozoa can be released under low ionic strength conditions, whereas the interaction of N‐acetyl‐β‐D‐glucosaminidase and β‐glucuronidase ...
Aguilera, Andrea Carolina   +4 more
openaire   +4 more sources

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