Role of N-glycosylation in oral cancer [PDF]
Oral squamous cell carcinoma represents more than 90% head and neck cancers with high incidence rate and morbidity. To date, little is known about the molecular mechanisms responsible for OSCC initiation and progression to advanced disease.
Bukhari, Samah
core
Rhabdomyosarcoma targeting with tuned porous silicon nanoparticles
We describe porous silicon nanoparticles (pSiNP) chemically functionalized with an analog of mannose 6‐phosphate (AMFA) and a porphyrin derivative to target aggressive pediatric Rhabdomyosarcoma (RMS) tumor cells.
Sofia Dominguez‐Gil+10 more
doaj +1 more source
Sortilin knock-down alters the expression and distribution of cathepsin D and prosaposin and up-regulates the cation-dependent mannose-6-phosphate receptor in rat epididymal cells. [PDF]
Aguilera AC+7 more
europepmc +1 more source
The GARP Complex Is Involved in Intracellular Cholesterol Transport via Targeting NPC2 to Lysosomes
Proper intracellular cholesterol trafficking is critical for cellular function. Two lysosome-resident proteins, NPC1 and NPC2, mediate the egress of low-density lipoprotein-derived cholesterol from lysosomes.
Jian Wei+10 more
doaj +1 more source
Herpes simplex viruses (HSV) use multiple and sequential receptors to enter host cells. HSV glycoprotein D (gD) has been implicated in binding to cellular receptors that facilitate virus penetration into cells. We used soluble forms of gD that were expressed in Chinese hamster ovary cells to characterize and identify a putative cellular receptor for ...
Kevin S. Dingwell+6 more
openaire +3 more sources
Recognition of human urine α-N-acetylglucosaminidase by rat hepatocytes. Involvement of receptors specific for galactose, mannose 6-phosphate and mannose [PDF]
Kurt Ullrich+3 more
openalex +1 more source
Glycosidases Interact Selectively With Mannose‐6‐Phosphate Receptors of Bull Spermatozoa
ABSTRACTGlycosidases may play a role in sperm maturation during epididymal transit. In this work, we describe the interaction of these enzymes with bull spermatozoa. We found that β‐galactosidase associated to spermatozoa can be released under low ionic strength conditions, whereas the interaction of N‐acetyl‐β‐D‐glucosaminidase and β‐glucuronidase ...
Aguilera, Andrea Carolina+4 more
openaire +4 more sources
Publisher Correction: Sortilin knock-down alters the expression and distribution of cathepsin D and prosaposin and up-regulates the cation-dependent mannose-6-phosphate receptor in rat epididymal cells. [PDF]
Aguilera AC+7 more
europepmc +1 more source
The endosomal concentration of a mannose 6-phosphate receptor is unchanged in the absence of ligand synthesis. [PDF]
Suzanne R. Pfeffer
openalex +1 more source
Divergent Impact of Enzyme Replacement Therapy on Human Cardiomyocytes and Enterocytes Affected by Fabry Disease: Correlation with Mannose-6-phosphate Receptor Expression. [PDF]
Frustaci A+8 more
europepmc +1 more source