Results 41 to 50 of about 93,264 (274)

HOPE Kids 2: Phase 3, Randomized Trial of Voxelotor in Children With SCD and Conditional Cerebral Blood Flow Velocities

American Journal of Hematology, EarlyView.
ABSTRACT Children with SCD have elevated stroke risk, correlated with cerebral blood flow velocity (CBFV). HOPE Kids 2 was a phase 3, multicenter, double‐blind, placebo‐controlled trial evaluating the effect of voxelotor on CBFV. Participants aged 2 to < 15 years with SCD (HbSS/HbSβ0) and conditional CBFV (170 to < 200 cm/s) were randomized 1:1 to ...
Halima Bello‐Manga, Shehu Umar Abdullahi, Hoda Hassab, Biobele Brown, Videlis Nduba, Jessie Githanga, Adeseye Michael Akinsete, Amal El‐Beshlawy, Diana Hanna, Catherine Segbefia, Iheanyi Okpala, Azza Tantawy, Bernhards Ogutu, Venée N. Tubman, Vivian Paintsil, Yasser Wali, Mohammed Essa, Paul Telfer, Sandy Dixon, Anne Hickman, Jennifer F. Doss, Mark W. Davis, Jeremy Rupon, Fenella J. Kirkham, R. Clark Brown, on behalf of the HOPE Kids 2 Investigators, Amal El‐Beshlawy, Mohamed Badr, Diana Hanna*, Hoda Hassab, Azza Tantawy, Vivian Paintsil, Catherine Segbefia, Raffaella Colombatti, Daniela Cuzzubbo, Silverio Perrotta, Jessie Githanga, Videlis Nduba, Bernhards Ogutu, Shehu Umar Abdullahi, Adeseye Michael Akinsete, Halima Bello‐Manga, Biobele Brown, Iheanyi Okpala, Yasser Wali, Mohammed Essa, Banu Kaya, Paul Telfer, Ofelia Alvarez, Natasha Archer, Shayla Bergmann, R Clark Brown, Andrew Campbell, Carlton Dampier*, Richard Hurwitz, Erin Jackson, Janet Kwiatkowski, Melissa M. McNaull*, Venée N. Tubman   +58 more
wiley   +1 more source

Differential Item Functioning Detection With the Mantel-Haenszel Procedure: The Effects of Matching Types and Other Factors

, 2015
The Mantel-Haenszel (MH) procedure is commonly used to detect items that function differentially for groups of examinees from various demographic and linguistic backgrounds—for example, in international assessments.
A. Socha, Christine E. DeMars, A. Zilberberg, H. Phan   +3 more
semanticscholar   +1 more source

Anteromedial Femoral Tunnel Placement Reduces Graft Failure Risk Without Affecting Rotational Stability in Anatomic Single‐Bundle Anterior Cruciate Ligament Reconstruction: A Systematic Review

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To compare clinical outcomes and graft failure between anatomical femoral tunnel (FT) placement at the central and anteromedial bundle (AMB) positions. Methods A systematic review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines.
Haitham Kamel Haroun, Amr Mohamed Abdelhady, Mohamed Abdallah Obied, Mostafa Aly Elabd   +3 more
wiley   +1 more source

Continuous analogues of Cochran-Mantel-Haenszel statistics

, 2012
Cochran-Mantel-Haenszel (CMH) statistics are reviewed and continuous analogues of the CMH general association and mean score statistics are given.
J C Rayner (13504090), D Best (13507168)
core   +1 more source

Association of ZC3HAV1 single nucleotide polymorphisms with the susceptibility of Vogt-Koyanagi-Harada Disease

BMC Medical Genomics, 2023
Background Polymorphisms of genes related to the immune response have been reported to confer susceptibility to Vogt-Koyanagi-Harada (VKH) disease. This study was carried out to determine whether zinc finger CCCH-type containing antiviral 1 (ZC3HAV1) and
Qiuying Wu, Zhenyu Zhong, Chunya Zhou, Qingfeng Cao, Guannan Su, Peizeng Yang   +5 more
doaj   +1 more source

Efficacy and Safety of Nanoencapsulated Sirolimus Plus Pegadricase: Results From the Randomized, Placebo‐Controlled Phase 3 Trials

Arthritis &Rheumatology, EarlyView.
Objective DISSOLVE I and II examined the efficacy and safety of nanoencapsulated sirolimus (NAS) plus pegadricase (NASP) in patients with uncontrolled gout (UG). Methods In these double‐blind, placebo‐controlled Phase 3 trials of NASP, patients were randomized 1:1:1 to infusions of high‐dose (HD) or low‐dose (LD) NAS plus pegadricase (HD NASP, LD NASP,
Herbert S. B. Baraf, Puja P. Khanna, Milan Petronijevic, Mamuka Lortkipanidze, Anand Patel, Kwabena Ayesu, Michael H. Pillinger, Atul Singhal, Joanna Sobierska, Jacquie Christie, Peter Traber, Rehan Azeem, Wesley DeHaan, Hugues Santin‐Janin, Bhavisha Desai, Alan Kivitz   +15 more
wiley   +1 more source

KETEPATAN METODE MANTEL-HAENSZAL, SIBTEST, DAN REGRESI LOGISTIK UNTUK MENDETEKSI DIFFERENTIAL ITEM FUNCTION

Jurnal Penelitian dan Evaluasi Pendidikan, 2013
Penelitian dilakukan untuk mengetahui (a) urutan ketepatan pendeteksian Differential Item Functioning (DIF) antara metode Mantel-Haenszel, the Simultanous Item Bias Test (SIBTEST), dan regresi logistik, (b) persentase kandungan DIF, Mantel-Haenszel ...
Budiyono Budiyono
doaj  

DIF analysis using the generalized Mantel Haenszel Method.

, 2018
DIF analysis using the generalized Mantel Haenszel Method.
Juan Ignacio Aragonés (5988377), María Teresa Coello (5988374), Cynthia McPherson Frantz (5988380), Laura Pasca (5988371)   +3 more
core   +1 more source

Deucravacitinib in Active Psoriatic Arthritis: Efficacy and Safety up to 52 Weeks From the Randomized, Double‐Blind, Phase 3 POETYK PsA‐2 Trial

Arthritis &Rheumatology, Accepted Article.
Objective To assess the efficacy and safety of deucravacitinib, an oral, selective tyrosine kinase 2 inhibitor, in patients with psoriatic arthritis (PsA) who were naive to biologic disease‐modifying antirheumatic drugs or received tumor necrosis factor inhibitors. Methods In the 52‐week (W), double‐blind, placebo‐controlled, phase 3 POETYK PsA‐2 study
Philip J. Mease, Vinod Chandran, April W. Armstrong, Ricardo Blanco, Alexis Ogdie, Evan L. Siegel, Alice B. Gottlieb, Xiaofeng Zeng, Diamant Thaçi, Mitsumasa Kishimoto, Hendrik Schulze‐Koops, Alan Kivitz, Eva Dokoupilová, Akimichi Morita, Eric M. Ruderman, Michael Plewinski, Kejia Wang, Caroline Sardinas, Eleni Vritzali, John Vaile, Atul Deodhar   +20 more
wiley   +1 more source

Metaanálisis: Efectividad del tratamiento a largo y corto plazo con albendazol para la neurocisticercosis intraparenquimatosa

Horizonte Médico, 2018
Objective: To determine the effectiveness of long- and short-term albendazole therapy in adults and children with cystic and transitional parenchymal neurocysticercosis confirmed by neuroimaging.
Teodoro Edmundo Jerves Serrano
doaj   +1 more source