Results 51 to 60 of about 369,419 (282)
Manual Training and Manual Labor [PDF]
The Elementary School Teacher, 1904 THE march of manual training in the educational world is rivaled by the retreat of manual labor in the industrial world. At first glance the general situation seems to be something of an anomaly. The tremendous development of machinery and applied science in the industrial world has crowded in between the brain and the hand, feeding on both ...
openaire +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
La enseñanza española de la historia y su dimensión Iberoamericana [PDF]
, 2012 La presencia de los países iberoamericanos es una cuestión que ha estado permanentemente asegurada en los libros de texto de la educación secundaria española desde la implantación del sistema educativo liberal, a mediados del siglo XIX, hasta la ...
Valls Montés, Rafael
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Telares manuales en la provincia de Badajoz [PDF]
, 1982 En número dedicado a: La provincia de ...
Timón Tiemblo, María Pía
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
El análisis de manuales y la identificación de problemas de investigación en Didáctica de las Matemáticas [PDF]
, 2009 La ambigüedad del signo radical es un problema con raíces históricas que ha quedado recogido en una tradición de enseñanza reflejada en los manuales escolares.
Gómez, Bernardo
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source