Results 61 to 70 of about 2,720 (255)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Revista Brasileira de História da Ciência, 2016 Este trabajo intenta aportar a comprender las condiciones en que la física fue enseñada en las primeras décadas del siglo XX en la escuela media Argentina.
Cecilia Von Reichenbach +1 more
doaj +1 more source
A MANUAL OF NEURASTHENIA [PDF]
The Journal of Nervous and Mental Disease, 1921 n ...
openaire +2 more sources
, 1983 A phenolic cart holding 3 mutually perpendicular search coils is moved through an luminum beam into the magnetic field. Coil voltages re integrated and digitized through a Data Translation 1712 ADC. The cart is controlled and the data is processed by an on-line PDP-11/05 computer.
Ito, A. +5 more
openaire +3 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Revista Mexicana de Historia de la Educación, 2016 Los manuales escolares han ocupado el centro de la actividad académica desde que la escuela existe como institución normalizada. Incluso en la actualidad, cuando emergen movimientos renovadores a favor de la incorporación de nuevos materiales, de la ...
Xosé Manuel Malheiro Gutiérrez
doaj +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Habilidades funcionales de niños, niñas y adolescentes con parálisis cerebral y su relación con el compromiso motor y la discapacidad intelectual en Argentina. [PDF]
Rev Fac Cien Med Univ Nac Cordoba, 2023 Ruiz Brunner MLM +9 more
europepmc +1 more source