Results 51 to 60 of about 35,682 (304)

Glozman, Mara y Karina Savio. (2019) Manual para estudiar textos académicos. Buenos Aires: NOVEDUC. Colección Universidad, 244 págs.

open access: yesQuintú Quimün, 2020
Desde su surgimiento hace ya casi cuatro décadas, con el retorno de la democracia a nuestro país, las materias dedicadas a la enseñanza de la lectura y la escritura en la universidad han constituido un espacio de producción de saberes tanto didácticos ...
Laura Eisner
doaj  

La docencia de ELE en Chile y el uso de manuales extranjeros en el aula [PDF]

open access: yesmarcoELE. Revista de Didáctica Español Lengua Extranjera, 2018
El presente estudio se centra en conocer la actuación docente en Chile respecto al uso de manuales en el aula. Se entrevistó a tres profesoras para conocer qué tipo de materiales y manuales utilizaban, y en el caso de que estos fueran extranjeros -como ...
Quirós Blanco, Gema
doaj  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

A Manual of Medicine [PDF]

open access: yesThe American Journal of the Medical Sciences, 1903
n ...
openaire   +5 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Los manuales de ELE editados en Rumanía en la década de los años '90. : el legado de los manuales comunistas [PDF]

open access: yes, 2021
Este estudio versa sobre los manuales de ELE que se utilizaron en el sistema educativo público de Rumanía en la década de los años ’90, tras la caída del régimen comunista.
Bran Rǎzvan
core  

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