Results 41 to 50 of about 11,850 (257)

How to expedite office work? – Jan Kościołek’s ways of rationalising office work

open access: yesArchiwa - Kancelarie - Zbiory, 2018
Jan Kościołek was a trained lawyer, a clerk of mid-war and post-war Poland, author of many publications. Almost all of them had one objective: to make works of offices more effective.
Marcin Smoczyński
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Role of professional motivation in the system of education of students in physical culture high schools. [PDF]

open access: yesPedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2012
The main approaches to the professional motivation formation in the system of education in the physical culture шт. high educational institutions have been determined in the article.
Stepanchenko N.I.
doaj  

Features of Educational Electronic Grade Development by Engineering Disciplines

open access: yesSHS Web of Conferences, 2018
Traditional teaching aids lose their relevance in connection with the introduction of a competence approach, therefore, it is necessary to introduce such manuals that will allow students to retain their mobility and productivity without losing the ...
Vaganova Olga I.   +4 more
doaj   +1 more source

Vilnius Printers’ Ornaments in the Second Half of the Eighteenth Century as a Source of the History of the Books

open access: yesKnygotyra, 2020
This article focuses on the 18th century printers’ ornaments as an important group of sources of the history of the book. Until now, most studies in Lithuanian had focused on the decorations of books from the 16th– 17th centuries as well as contemporary ...
Ina Kažuro
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

A Review on Radiation Damage in Concrete for Nuclear Facilities: From Experiments to Modeling

open access: yesModelling and Simulation in Engineering, 2016
Concrete is a relatively cheap material and easy to be cast into variously shaped structures. Its good shielding properties against neutrons and gamma-rays, due to its intrinsic water content and relatively high-density, respectively, make it the most ...
Beatrice Pomaro
doaj   +1 more source

Deep Learning-Based AI-Assisted Visual Inspection Systems for Historic Buildings and their Comparative Performance with ChatGPT-4O [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Historical buildings and monuments are typically subject to degradation over time due to the passage of time and constant exposure to external agents. The use of artificial intelligence (AI) to support the work of conservation and restoration specialists
M. Mishra   +7 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

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