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How to expedite office work? – Jan Kościołek’s ways of rationalising office work
Jan Kościołek was a trained lawyer, a clerk of mid-war and post-war Poland, author of many publications. Almost all of them had one objective: to make works of offices more effective.
Marcin Smoczyński
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
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Role of professional motivation in the system of education of students in physical culture high schools. [PDF]
The main approaches to the professional motivation formation in the system of education in the physical culture шт. high educational institutions have been determined in the article.
Stepanchenko N.I.
doaj
Features of Educational Electronic Grade Development by Engineering Disciplines
Traditional teaching aids lose their relevance in connection with the introduction of a competence approach, therefore, it is necessary to introduce such manuals that will allow students to retain their mobility and productivity without losing the ...
Vaganova Olga I. +4 more
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This article focuses on the 18th century printers’ ornaments as an important group of sources of the history of the book. Until now, most studies in Lithuanian had focused on the decorations of books from the 16th– 17th centuries as well as contemporary ...
Ina Kažuro
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
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A Review on Radiation Damage in Concrete for Nuclear Facilities: From Experiments to Modeling
Concrete is a relatively cheap material and easy to be cast into variously shaped structures. Its good shielding properties against neutrons and gamma-rays, due to its intrinsic water content and relatively high-density, respectively, make it the most ...
Beatrice Pomaro
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Deep Learning-Based AI-Assisted Visual Inspection Systems for Historic Buildings and their Comparative Performance with ChatGPT-4O [PDF]
Historical buildings and monuments are typically subject to degradation over time due to the passage of time and constant exposure to external agents. The use of artificial intelligence (AI) to support the work of conservation and restoration specialists
M. Mishra +7 more
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Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
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