Results 51 to 60 of about 3,908,002 (290)

Leveraging Additive Manufacturing and Reverse Engineering for Circular Economy-Driven Remanufacturing of Hydraulic Drive System Components

open access: yesApplied Sciences, 2023
In response to the imperative of sustainability and resource efficiency, this article introduces an innovative framework for the remanufacture of hydraulic drive system components, firmly rooted in the tenets of the circular economy.
Alexandru-Polifron Chiriță   +4 more
doaj   +1 more source

CCT4 promotes tunneling nanotube formation

open access: yesFEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto   +3 more
wiley   +1 more source

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

open access: yesFEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji   +3 more
wiley   +1 more source

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

open access: yesFEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera   +4 more
wiley   +1 more source

Engineering and Environmental Analysis of Additive Manufacturing in the Food Industry

open access: yesEngineering Proceedings
In the context of increasing demands for sustainability and individualization in the food industry, additive manufacturing (AM) represents a promising technology with the potential to transform manufacturing processes.
Valentina Nikolova-Alexieva   +3 more
doaj   +1 more source

Data-driven engineering framework with AI algorithm of Ginkgo Folium tablets manufacturing

open access: yesActa Pharmaceutica Sinica B, 2023
Smart manufacturing still remains critical challenges for pharmaceutical manufacturing. Here, an original data-driven engineering framework was proposed to tackle the challenges.
Lijuan Ma   +10 more
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

From Discovery to Mass Production: A Perspective on Bio-Manufacturing Exemplified by the Development of Statins

open access: yesEngineering, 2023
The increasingly complex molecular structures and high requirements of advanced industries are triggering a transformation in chemical production modes. Bio-manufacturing provides efficient strategies and brings the advantages of high atomic economy, few
Xiao-Ling Tang   +5 more
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Additive Manufacturing of Hydrogels in Tissue Engineering [PDF]

open access: yesJournal of Chemistry Letters
Systematically review the development of 3D printing, describe the area of 3D printing hydrogel research, and describe the development of 3D printing hydrogel.
Md. Shyeed   +5 more
doaj   +1 more source

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