Kinematics optimization for high positioning accuracy of a 4-DOF parallel manipulator for semiconductor applications [PDF]
, 2003 The end-effector kinematics error of a manipulator is caused by variations in machining accuracy of linkages. In most manipulators, the structural design results in an error magnification from the linkage variation to the end-effector position.
Cheung, WFJ, Hung, YS
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Cloud-Based Machine Learning Methods for Parameter Prediction in Textile Manufacturing
SensorsIn traditional textile manufacturing, downstream manufacturers use raw materials, such as Nylon and cotton yarns, to produce textile products. The manufacturing process involves warping, sizing, beaming, weaving, and inspection.
Ray-I Chang, Jia-Ying Lin, Yu-Hsin Hung
doaj +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Capture of manufacturing uncertainty in turbine blades through probabilistic techniques
, 2008 Efficient designing of the turbine blades is critical to the performance of an aircraft engine. An area of significant research interest is the capture of manufacturing uncertainty in the shapes of these turbine blades.
Keane, Andy +2 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
DETECTION OF PROCESS ERRORS OF ADDITIVE MANUFACTURING
MM Science JournalAdditive manufacturing has the potential to revolutionize the production of complex and adapted parts, but is prone to manufacturing errors, ranging from minor inaccuracies and mechanical failures to complete failures associated with the production of rejects.
PETER GABSTUR +2 more
openaire +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Kinematic Compensation Algorithm for Reducing Errors in a Closed-Loop Manufacturing System
IEEE AccessDuring the manufacturing process of a piece, different factors influence the process so that errors of a systematic and random nature are added, affecting both the dimensions and the final geometry.
Cristhian I. R. Jaimes +2 more
doaj +1 more source
An evaluation of the welfare effects of United States meat import quotas using the concept of economic surplus : a thesis presented in partial fulfilment of the requirements for the degree of Master of Agricultural Science in Agricultural Economics and Marketing at Massey University [PDF]
, 1974 The original objective of this study was to estimate the effect of United States Meat Import Quotas on economic welfare in the United States and New Zealand.
Bryant, L. I
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