Results 71 to 80 of about 816,445 (307)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
On Export-Led Growth: Is Manufacturing Exports a New Engine of Growth for Bangladesh? [PDF]
The study attempts to empirically verify the export-led growth hypothesis for Bangladesh. In this context, we examine whether manufacturing exports has become a new engine of export-led growth replacing total exports, as claimed by the so-called de novo ...
M.A.Hossain
core
Fault-tolerance thresholds for the surface code with fabrication errors [PDF]
, 2017 The construction of topological error correction codes requires the ability to fabricate a lattice of physical qubits embedded on a manifold with a non-trivial topology such that the quantum information is encoded in the global degrees of freedom (i.e ...
Anwar, Hussain +4 more
core +3 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
MathematicsManufacturing condition monitoring in low-frequency sensing environments presents significant challenges for traditional anomaly detection methods, which depend on dense temporal observations or instantaneous thresholding.
Jinwoo Song, Heung Soo Kim
doaj +1 more source
Apartment Security: A Note on Gated Access and Rental Rates [PDF]
This study empirically examines the dynamics of the private industrial market in Singapore using a Vector Error Correction Model (VECM), which is derived based on the theoretical framework of an extended accelerator investment model.
Tien Foo Sing
core
Reengineering Biomedical Engineering Curricula: A New Product Development Approach [PDF]
, 2002 Product development engineers in medical industries have created design control procedures to ensure high quality designs that are as error-free as possible.
Ropella, Kristina M. +2 more
core +1 more source
Dampak Keterbukaan Perdagangan dan Kinerja Manufaktur di Indonesia [PDF]
, 2015 This study aims to analyze the impact of trade openness on the performance of manufacturing in Indonesia. In the study, performance and manufacturing growth indicated by the index of competitiveness and manufacturing added value.
Anggraeni, L. (Lukytawati) +2 more
core +2 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Modèle des interactions dynamiques [PDF]
, 2014 In robotic-based machining, an interaction between the workpiece and technological tool causes essential deflections that significantly decrease the manufacturing accuracy.
CARO, Stéphane +2 more
core +1 more source