Results 91 to 100 of about 9,455,846 (272)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Cell Transplantation, 2018 We examined the effects of human umbilical cord-derived mesenchymal stem cells (HUMSCs) in Wharton’s jelly on ovariectomy (OVX)-induced osteoporosis by using in vitro and in vivo experiments.
Yu-Show Fu +7 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
‘Epitaph' on Grizzel Grim: a newly-discovered manuscript in the hand of Robert Burns [PDF]
, 2015 Describes and reproduces a newly-discovered Burns manuscript, with notes and numerical calculations relating to his work as an Excise Officer, and the four-line 'Epitaph' on Grizzel Grim (Kinsley II:926); discusses its publication history, attribution to
Henderson, Jonathan +2 more
core +1 more source
Lothar’s manuscripts, manuscripts for Lothar, manuscripts of Lothar’s time
, 2022 This paper aims to give an account of some of the manuscripts related to Lothar. In its first section an attempt is made at retracing a set of books that could have belonged to Lothar’s library, nowadays known only from secondary sources. In the second section some display codices are discussed, either commissioned by Lothar, or dedicated to him, such ...
openaire +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Sialkoti paper used by Pahari artists: raw materials and fibre analysis
Heritage ScienceThis study aims to characterise the so-called Sialkoti paper used to produce Pahari drawings preserved today in the Wereldmuseum in Leiden (Netherlands) (WML). These works originate from the Punjab Hills in India (today Himachal Pradesh) and are commonly
Amélie Couvrat Desvergnes +1 more
doaj +1 more source
Poznańskie Studia Polonistyczne. Seria Literacka, 2010 The Library of the Poznań Society of Friends of Arts and Sciences has been recently enriched by the accession of the manuscript “Poetical texts from the first half of the nineteenth century”.
Joanna Pietrowicz
doaj +1 more source
Data-driven modelling of biological multi-scale processes
, 2015 Biological processes involve a variety of spatial and temporal scales. A holistic understanding of many biological processes therefore requires multi-scale models which capture the relevant properties on all these scales.
Hasenauer, Jan +3 more
core +1 more source