Results 81 to 90 of about 1,535,370 (308)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Federica Buttò, Le « Tristan en prose » du ms. BnF français 756 : texte et étude

open access: yesPerspectives Médiévales
Sixteen years after the last publication of a volume of the Tristan en prose (2007), this work completes this edition based on the manuscript Paris, Bibliothèque nationale de France, français 757, by making available the first half of the prose romance ...
Federica Buttò
doaj   +1 more source

Basel, Universitätsbibliothek, A IX 23 : Composite manuscript (theology)

open access: yes
This manuscript from the library of the lay brothers of the Carthusian monastery in Basel consists of various parts that are bound together. It was meant as a devotional book for the lay brothers and contains various basic texts in German translation ...

core   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Basel, Universitätsbibliothek, D IV 10 : Composite manuscript (chronicles)

open access: yes
The core of this manuscript from the Carthusian Monastery of Basel is a copy of the Flores temporum, a Latin world chronicle from the 13th century that was widely used in Alemannic areas.
Heinrich Arnoldi   +4 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Tradisi lisan, naskah, dan sejarah Sebuah catatan politik kebudayaan

open access: yesWacana: Journal of the Humanities of Indonesia, 2005
Tradition can be seen from two different perspectives, those of literacy (writing system) and of oral tradition. Recently, some intellectuals have shown interest in oral tradition as academic study in some universities.
I Nengah Duija
doaj   +1 more source

Cologny, Fondation Martin Bodmer, Cod. Bodmer 706 : Kalpasūtra, i.e. "Book of rituals"

open access: yes
This unbound manuscript contains one of the most copied texts of the Śvetāmbara Jaina tradition, the Kalpasūtra, which was very popular all over India from the 14th century on. It is a collection of life stories of the great Tīrthaṅkāras.

core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

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