Results 51 to 60 of about 381,026 (309)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Study on establishment of Body of Knowledge of Taiwan's Traditional Wooden Structure Technology [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2015 The timber technology of the Taiwan traditional architecture is brought by the immigrants in the Southern Fujian of China in the early, which has been inherited for a hundred years.
M. T. Huang +3 more
doaj +1 more source
Operating System and Scheduling for Future Multi-core and Many-Core Platforms
, 2017 In this chapter, an overview is made on the limitations of the nowadays OS support for multicore systems, when applied to the future and emerging many-core, massively parallel and distributed platforms.
CUCINOTTA, TOMMASO +4 more
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
SENECA: building a fully digital neuromorphic processor, design trade-offs and challenges
Frontiers in Neuroscience, 2023 Neuromorphic processors aim to emulate the biological principles of the brain to achieve high efficiency with low power consumption. However, the lack of flexibility in most neuromorphic architecture designs results in significant performance loss and ...
Guangzhi Tang +10 more
doaj +1 more source
Optimizing Streaming Parallelism on Heterogeneous Many-Core Architectures [PDF]
IEEE Transactions on Parallel and Distributed Systems, 2020 As many-core accelerators keep integrating more processing units, it becomes increasingly more difficult for a parallel application to make effective use of all available resources. An effective way for improving hardware utilization is to exploit spatial and temporal sharing of the heterogeneous processing units by multiplexing computation and ...
Peng Zhang 0061 +5 more
openaire +3 more sources
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
A Message Passing Many-Core Architecture for an Asynchronous Graph Programming Model
, 2022 Noticeable improvements in processor performance have been achieved by researching programming models, control flow parallelization, general architecture, memory access, and code compilation [53][4].
Cook, Sebastien
core +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source