Results 211 to 220 of about 113,529 (264)

A Fully Defined GelMA‐Based Matrix Allows Fine Tuning of Tissue‐Relevant Biomechanical and Biochemical Cues for Organoid Culture

Advanced Healthcare Materials, EarlyView.
A fully defined GelMA‐based ECM platform integrates tunable tissue‐relevant stiffness with laminin–entactin biochemical supplementation to support mouse small intestinal organoid growth. Coordinated control of mechanical and biochemical cues promotes robust proliferation, budding morphogenesis, differentiation, and passaging, providing a reproducible ...
Junyi Liu, Su Su Htwe, Lay Poh Tan, Yen Choo   +3 more
wiley   +1 more source

Phospho-Proteomics Identifies D-Group MAP Kinases as Substrates of the <i>Arabidopsis</i> Tyrosine Phosphatase RLPH2. [PDF]

Plant Direct
Labandera AM, Toth R, Mitchell S, Johnson JJ, Kurucz B, Puyaubert J, Baudouin E, Uhrig RG, Moorhead GB.   +8 more
europepmc   +1 more source

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

Advanced Healthcare Materials, EarlyView.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer, Bryan Calder Ackermann, Anna Stoß, Niklas Junker, Ludwig Geisweid, Sabrina Wohlfart, Jonathan Herth, Simon William Pohl, Manuel Ben Böhmann, André Schulz, Victor Aristide Augustin, Gerd Uwe Auffarth, Philipp Uhl   +12 more
wiley   +1 more source

Analysis of CacyBP/SIP, ERK1/2, and p38 Expression in Low- and High-Grade Papillary Urothelial Carcinoma. [PDF]

Cancer Med
Domian N, Młynarczyk G, Kasacka I.
europepmc   +1 more source

Identification and Validation of an Inhibitor of the Protein Kinases PIM and DYRK. [PDF]

J Med Chem
Bencze G, Venkataramani P, Elkayam E, Rivera KD, Garg A, Szabadakai I, Orfi L, Joshua-Tor L, Pappin DJ, Tonks NK.   +9 more
europepmc   +1 more source

Mapping of dynamic allostery within p38 alpha kinase via network analyses and NMR spectroscopy

Linser R, Acharyya S, Weisner J, Bernardi R.   +3 more
europepmc   +1 more source

Kinase inhibition rewires the HLA-I immunopeptidome in chronic myeloid leukemia. [PDF]

iScience
Venafra V, Wahle M, Massacci G, Bica V, Chiusolo P, Mougiakakos D, Boettcher M, Fischer T, Perfetto L, Mann M, Sacco F.   +10 more
europepmc   +1 more source

Dissecting the Phospho-Regulatory Landscape of Protein Kinase N1 (PKN1) and Its Downstream Signaling: Functional Insights into the Activity-Dependent and Disease-Relevant Phosphosites. [PDF]

Int J Mol Sci
Kammarambath SR, Dcunha L, Gopalakrishnan AP, Gautam YS, Basha FA, Shivamurthy PB, Madar IH, Raju R.   +7 more
europepmc   +1 more source

Structural and mechanistic basis of ubiquitous bacterial kinase signaling identifies PorX as a noncanonical substrate in Porphyromonas gingivalis. [PDF]

J Biol Chem
Saran A, Yang Z, Wang Z, Harris JNC, Vahidi S, Zeytuni N.   +5 more
europepmc   +1 more source