Results 1 to 10 of about 30,825 (164)
Calcium signaling and postsynaptic density dynamics: the roles of calmodulin in synaptic protein regulation [PDF]
Frontiers in Molecular NeuroscienceCalcium signaling in neuronal cells is the principal mechanism underlying learning and synaptic plasticity, whereas the postsynaptic density (PSD) is an important center where calcium-dependent processes are organized and regulated.
Keyaa Dilip Shah, Yonghong Zhang
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Specificity of calcium/calmodulin-dependent protein kinases in mouse egg activation. [PDF]
Cell Cycle, 2014 CaMKIIγ, the predominant CaMKII isoform in mouse eggs, controls egg activation by regulating cell cycle resumption. In this study we further characterize the involvement and specificity of CaMKIIγ in mouse egg activation. Using exogenous expression of different cRNAs in Camk2g(-/-) eggs, we show that the other multifunctional CaM kinases, CaMKI, and ...
Medvedev S, Stein P, Schultz RM.
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Frontiers in Plant Science, 2015 Calcium and calmodulin-dependent protein kinase (CCaMK) is a member of calcium/calmodulin-dependent protein kinase superfamily and is essential to microbe- plant symbiosis.
Ji-Peng eWang +3 more
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Phosphosite-specific co-regulation networks of MELK kinase: insights from integrative global phosphoproteomes [PDF]
Journal of Genetic Engineering and BiotechnologyMaternal embryonic leucine zipper kinase (MELK) is a serine/threonine kinase frequently overexpressed in aggressive cancers, yet the precise mechanisms governing its activation and signaling specificity remain poorly understood.
Noreen A Khan +7 more
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Parasites & Vectors, 2021 Background Echinococcosis, which is caused by the larvae of cestodes of the genus Echinococcus, is a parasitic zoonosis that poses a serious threat to the health of humans and animals globally.
Hai-Jun Gao +9 more
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Calcium/Calmodulin–Dependent Protein Kinase II in Cerebrovascular Diseases [PDF]
Translational Stroke Research, 2021 AbstractCerebrovascular disease is the most common life-threatening and debilitating condition that often leads to stroke. The multifunctional calcium/calmodulin-dependent protein kinase II (CaMKII) is a key Ca2+ sensor and an important signaling protein in a variety of biological systems within the brain, heart, and vasculature.
Xuejing Zhang +4 more
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Cell Communication and Signaling, 2022 Background A major goal in the discovery of cellular signaling networks is to identify regulated phosphorylation sites (“phosphosites”) and map them to the responsible protein kinases.
Kirby T. Leo +5 more
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Inhibition of Calcium/Calmodulin-Dependent Protein Kinase Kinase β and Calcium/Calmodulin-Dependent Protein Kinase IV Is Detrimental in Cerebral Ischemia [PDF]
Stroke, 2013 Background and Purpose— Elevation of intracellular calcium was traditionally thought to be detrimental in stroke pathology. However, clinical trials testing treatments that block calcium signaling have failed to improve outcomes in ischemic stroke.
Louise D, McCullough +7 more
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Applied Sciences, 2022 Gap junctions, mainly formed by Gja1 (Connexin43), play an essential role in the regulation of proliferation and differentiation of spermatogonia in the testis.
Mustapha Najih +4 more
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Ser-Thr phosphatases in the rat brain that dephosphorylate phospho-Ser(1291)-GluN2A subunit of glutamate receptor [PDF]
The Ukrainian Biochemical Journal, 2023 N-methyl-D-aspartate receptors (NMDARs), are one of the major ionotropic glutamate receptors found in excitatory synapses which play a key role in glutamatergic synaptic transmission.
R. R. Prabhu
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