Results 21 to 30 of about 30,912 (250)
Plants, 2020 Copper induces an oxidative stress condition in the marine alga Ulva compressa that is due to the production of superoxide anions and hydrogen peroxide, mainly in organelles.
Alejandra Moenne +5 more
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Redox Regulation of the Calcium/Calmodulin-dependent Protein Kinases
Journal of Biological Chemistry, 2004 Reactive oxygen intermediates (ROI) have been viewed traditionally as damaging to the cell. However, a predominance of evidence has shown that ROI can also function as important activators of key cellular processes, and ROI have been shown to play a vital role in cell signaling networks.
Christopher J, Howe +3 more
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Frontiers in Physiology, 2020 The traditional view of ventricular excitation and conduction is an all-or-nothing response mediated by a regenerative activation of the inward sodium channel, which gives rise to an essentially constant conduction velocity (CV).
Alexey V. Zaitsev, Mark Warren
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Marine Drugs, 2018 Perfluorooctane sulfonate (PFOS), a stable fluorosurfactant, causes endoplasmic reticulum (ER) stress in the brain. This study was designed to investigate whether a phycoerythrin-derived peptide of Pyropia yezoensis (PYP) reduces PFOS-induced ER stress ...
Jeong Hwan Oh +2 more
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Small-Molecule Inhibitor Targeting Protein Kinase D: A Potential Therapeutic Strategy
Frontiers in Oncology, 2021 The protein kinase D (PKD) family is a family of serine-threonine kinases that are members of the calcium/calmodulin-dependent kinase (CaMK) superfamily.
Die Lv +7 more
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Activation of calcium/calmodulin-dependent kinase II following bovine rotavirus enterotoxin NSP4 expression [PDF]
Iranian Journal of Basic Medical Sciences, 2015 Objective(s): The rotavirus nonstructural protein 4 (NSP4) is responsible for the increase in cytoplasmic calcium concentration through a phospholipase C-dependent and phospholipase C-independent pathways in infected cells. It is shown that increasing of
Hadi Razavinikoo +5 more
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PLoS Pathogens, 2011 Apicomplexan parasites depend on the invasion of host cells for survival and proliferation. Calcium-dependent signaling pathways appear to be essential for micronemal release and gliding motility, yet the target of activated kinases remains largely ...
Thomas Nebl +7 more
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In Depth Analysis of Kinase Cross Screening Data to Identify CAMKK2 Inhibitory Scaffolds
Molecules, 2020 The calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) activates CAMK1, CAMK4, AMPK, and AKT, leading to numerous physiological responses. The deregulation of CAMKK2 is linked to several diseases, suggesting the utility of CAMKK2 inhibitors ...
Sean N. O’Byrne +11 more
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Ca2+ Signaling and Src Functions in Tumor Cells
Biomolecules, 2023 Signaling by calcium ion (Ca2+) plays a prominent role in cell physiology, and these mechanisms are frequently altered in tumor cells. In this review, we consider the interplay of Ca2+ signaling and the functions of the proto-oncogene non-receptor ...
Antonio Villalobo
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New isoforms of multifunctional calcium/calmodulin‐dependent protein kinase II [PDF]
FEBS Letters, 1993 Calcium/calmodulin dependent protein kinase II (CaM kinase II) seems to act as an important regulator of intracellular signal transmission. Four subtypes, termed α to δ, have been cloned; some of them can exist as different splicing variants. All these isoforms share a great overall homology, and they contain 3 areas of low homology. We have identified
Mayer, Peter +3 more
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