Results 11 to 20 of about 30,912 (250)

The role of calcium and CaMKII in sleep

open access: yesFrontiers in Systems Neuroscience, 2022
Sleep is an evolutionarily conserved phenotype shared by most of the animals on the planet. Prolonged wakefulness will result in increased sleep need or sleep pressure. However, its mechanisms remain elusive. Recent findings indicate that Ca2+ signaling,
Yuyang Wang   +4 more
doaj   +1 more source

Са2+- та Са2+-кальмодулін-залежні протеїнкінази – потенційні регулятори структури і функцій мікротрубочок у рослин

open access: yesФактори експериментальної еволюції організмів, 2017
Aim. Evaluate involvement of calcium/calmodulin-dependent protein kinases in regulation of plant microtubules using bioinformatic and structural biological methods. Methods. Sequences of tubulins isoforms was taken from UniProtKB.
D. O. Novozhylov   +4 more
doaj   +1 more source

Ca2+/CaM binding to CaMKI promotes IMA-3 importin binding and nuclear translocation in sensory neurons to control behavioral adaptation

open access: yeseLife, 2021
Sensory and behavioral plasticity are essential for animals to thrive in changing environments. As key effectors of intracellular calcium signaling, Ca2+/calmodulin-dependent protein kinases (CaMKs) can bridge neural activation with the many regulatory ...
Domenica Ippolito   +2 more
doaj   +1 more source

Functional, genetic and bioinformatic characterization of a calcium/calmodulin kinase gene in Sporothrix schenckii

open access: yesBMC Microbiology, 2007
Background Sporothrix schenckii is a pathogenic, dimorphic fungus, the etiological agent of sporotrichosis, a subcutaneous lymphatic mycosis. Dimorphism in S.
Rodriguez-del Valle Nuri   +3 more
doaj   +1 more source

Calcium/Calmodulin-Dependent Protein Kinase II: An Unforgettable Kinase [PDF]

open access: yesThe Journal of Neuroscience, 2004
Since the time neuroscientists first recognized that biochemical events inside neurons could influence the function of the brain, there have been people looking for “memory molecules.” This elusive ion, small molecule, protein, or nucleic acid would be the keystone on which memory was built;
openaire   +2 more sources

Protein phosphorylation pattern in the immune cells of leprosy affected individuals

open access: yesJournal of Infection in Developing Countries, 2008
Background: Leprosy is an infectious disease in which the susceptibility to the pathogen Mycobacterium leprae and the clinical manifestations are attributed to host immune cell response.
Karuna Devi Sagili   +5 more
doaj   +3 more sources

Mitogen‐Activated Protein Kinase and Intracellular Polyamine Signaling Is Involved in TRPV1 Activation–Induced Cardiac Hypertrophy

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundThe transient receptor potential vanilloid type 1 (TRPV1) is expressed in the cardiovascular system, and increased TRPV1 expression has been associated with cardiac hypertrophy.
Mai Chen   +6 more
doaj   +1 more source

Comparative transcriptome analysis reveals resistant and susceptible genes in tobacco cultivars in response to infection by Phytophthora nicotianae

open access: yesScientific Reports, 2021
Phytophthora nicotianae is highly pathogenic to Solanaceous crops and is a major problem in tobacco production. The tobacco cultivar Beihart1000-1 (BH) is resistant, whereas the Xiaohuangjin 1025 (XHJ) cultivar is susceptible to infection.
He Meng   +13 more
doaj   +1 more source

Targeting of calcium/calmodulin-dependent protein kinase II [PDF]

open access: yesBiochemical Journal, 2004
Calcium/calmodulin-dependent protein kinase II (CaMKII) has diverse roles in virtually all cell types and it is regulated by a plethora of mechanisms. Local changes in Ca2+ concentration drive calmodulin binding and CaMKII activation. Activity is controlled further by autophosphorylation at multiple sites, which can generate an autonomously active form
openaire   +2 more sources

Static compression regulates OPG expression in periodontal ligament cells via the CAMK II pathway

open access: yesJournal of Applied Oral Science, 2015
Objective This study aimed to investigate the potential role of CAMK II pathway in the compression-regulated OPG expression in periodontal ligament cells (PDLCs).
YI Jianru   +5 more
doaj   +1 more source

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