Results 321 to 330 of about 1,043,830 (367)

Regulation of FOXL2 gene in ovarian granulosa cell tumor by JNK inhibitor. [PDF]

Sci Rep
Zhang Y, Wang Y, Gu Y, Liu Y, Liu G, Wu J, Bai N.   +6 more
europepmc   +1 more source

Toward Personalized Stationary Chromatography Phases: Equipping Commercial Silica Phases with Selected Peptide‐Based Binding Domains to Tailor Affinity

Advanced Materials Interfaces, EarlyView.
The 7‐mer peptide motifs QFFLFFQ, QFFEFFQ, and QFQQSFF, known as good, medium, and poor binders for the photosensitizers m‐THPC and Chlorin E6 are covalently immobilized on commercial amino‐functionalized silica particles by inverse electron‐demand Diels‐Alder ligation.
Steffen A. Busche, Lukas D. Bangert, Raoul D. Brand, Tommy Kröger, Enrico Heyl, Hans G. Börner   +5 more
wiley   +1 more source

Inferring kinase-phosphosite regulation from phosphoproteome-enriched cancer multi-omics datasets. [PDF]

Brief Bioinform
Cheng H, Liang Z, Wu Y, Hu J, Cao B, Liu Z, Liu B, Cheng H, Liu ZX.   +8 more
europepmc   +1 more source

Investigating the Potential for Label‐Free Detection of Cell Apoptosis through Terahertz Nano‐Metasurfaces

Advanced Photonics Research, EarlyView.
This study demonstrates a label‐free optical method to monitor cells using a terahertz metasurface‐based biosensing platform. The obtained terahertz signal change for the cell‐contained nanoslots before and after external stimulus is analyzed in terms of transmittance and frequency shift, dynamically representing the cell apoptosis process.
Yeeun Roh, Jisung Kwak, Sang Jun Sim, Hyun Seok Song, Minah Seo   +4 more
wiley   +1 more source

A Selective MAP3K1 Inhibitor Facilitates Discovery of NPM1 as a Member of the Network. [PDF]

Molecules
Boghean L, Singh S, Mangalaparthi KK, Kizhake S, Umeta L, Wishka D, Grothaus P, Pandey A, Natarajan A.   +8 more
europepmc   +1 more source

Disintegration of the KITENIN/ErbB4 Functional Complex by the Flavonoid Hispidulin Suppresses Colorectal Cancer Progression

Advanced Therapeutics, EarlyView.
Hispidulin disrupts the KITENIN/ErbB4 oncogenic complex and inhibits KITENIN‐mediated AP‐1 activity, cell invasion, and aerobic glycolysis. It also suppresses the production of cancer‐associated metabolites and downregulates transcriptional regulators downstream of the KITENIN complex.
Mücahit Varlı, Songjin Oh, Eunae Kim, Barış Gökalsın, Nüzhet Cenk Sesal, Kyung Keun Kim, Man Jeong Paik, Hangun Kim   +7 more
wiley   +1 more source

miR-369-3p Ameliorates Inflammation and Apoptosis in Intestinal Epithelial Cells via the MEK/ERK Signaling Pathway. [PDF]

Int J Mol Sci
Scalavino V, Piccinno E, Giannelli G, Serino G.   +3 more
europepmc   +1 more source

Immune Checkpoint PD‐L1 Modulates Retinal Microglial Activation to Alleviate Vascular Leakage in Choroidal Neovascularization via ERK

Advanced Science, EarlyView.
PD‐L1 limits neuroinflammation in neovascular AMD by modulating microglial activation. Its deficiency exacerbates vascular leakage and choroidal neovascularization (CNV) via ERK signaling, while enhancing PD‐L1 reduces inflammation and neovascularization. Targeting PD‐L1 may offer a novel immunomodulatory strategy for NVAMD.
Yue Zou, Junliang Jiang, Yunqin Li, Xinyi Ding, Qiuping Tong, Ying Shi, Lei Xiao, Ling Chen   +7 more
wiley   +1 more source

The Yeast Gsk-3 Kinase Mck1 Is Necessary for Cell Wall Remodeling in Glucose-Starved and Cell Wall-Stressed Cells. [PDF]

Int J Mol Sci
Zhang F, Tang Y, Zhou H, Li K, West JA, Griffin JL, Lilley KS, Zhang N.   +7 more
europepmc   +1 more source

Reanalysis of cryo-EM data reveals ALK-cytokine assemblies with both 2:1 and 2:2 stoichiometries. [PDF]

PLoS Biol
Felix J, De Munck S, Bazan JF, Savvides SN.   +3 more
europepmc   +1 more source