Results 41 to 50 of about 1,138 (94)

Identification of heat shock transcription factor gene families in sunflower and their expression profiles under abiotic stress(向日葵热激转录因子基因家族鉴定及其在非生物胁迫下的表达分析)

浙江大学学报. 农业与生命科学版
Heat shock transcription factor (HSF) is widely distributed among plants and plays important roles in multiple transcriptional regulatory pathways, particularly in heat stress signaling and other stress responses.
宋慧芳(SONG Huifang), 薛宏宇(XUE Hongyu), 王茜(WANG Xi), 卢俊洁(LU Junjie), 李晨雨(LI Chenyu), 刘阿克(LIU Ake)   +5 more
doaj   +1 more source

番茄红素对脂多糖诱导巨噬细胞炎症反应的作用及其分子机制

Zhongshan Daxue xuebao. Yixue kexue ban, 2011
【目的】 探讨番茄红素对脂多糖(LPS)所诱导的RAW264.7巨噬细胞炎症因子生成的影响及其作用的分子机制【方法】 分别用1510 μmol/L 的番茄红素孵育细胞1 h,再用1 μg/mL LPS 处理细胞不同时间,分别用Griess法和ELISA法检测RAW264.7巨噬细胞培养基中NO及IL-6的含量,用Western-blot检测核因子-κB(NF-κB) p65磷酸化和非磷酸化I-κBα丝裂原活化蛋白激酶(MAPKs)的蛋白表达量【结果】 番茄红素能有效地降低炎性因子NO和IL-6分泌 ...
doaj  

基于网络药理学探索梅花草提取物抑制脑胶质瘤的作用机制

Zhongguo shiyan zhenduanxue
目的 运用网络药理学技术结合细胞及动物实验探讨梅花草提取物抑制脑胶质瘤恶性增殖的作用机制。方法 通过中药系统药理学分析平台(TCMSP)数据库筛选梅花草的有效化合物，使用OMIM、Genecards、Pubchem等数据库预测梅花草有效化合物对脑胶质瘤的潜在作用靶点，应用Cytoscape 3.9.1和STRING 11.5数据库构建化合物-靶点网络、蛋白质互作(PPI),筛选出核心基因，运用DAVID 6.8数据库对靶点进行基因本体(GO)的富集分析和京都基因与基因组百科全书(KEGG)的通路富集分析，
王睿君, 马宇衡, 王儒帅, 何占彪   +3 more
doaj  

[Research progress on the quercetin target role and signaling pathway in anti-liver fibrosis]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Zhao RQ, Liu HY, Yan JM, Hao Y, Ding YX, Zhang F, Zhou RM, Zhao R, Bai F, Bai WF.   +9 more
europepmc   +1 more source

TREM-1在细菌性化脓性角膜炎中的作用及其分子机制

Zhongshan Daxue xuebao. Yixue kexue ban, 2012
【目的】 探讨髓样细胞诱发受体1(TREM-1)在铜绿假单胞菌(PA)感染角膜炎中的作用及其分子机制。【方法】为了揭示TREM-1在细菌性角膜炎中的作用,我们建立了PA角膜炎小鼠模型和PA感染的腹腔巨噬细胞模型,real-time PCR和免疫荧光法检测感染前后TREM-1的表达水平;用丝裂原活化蛋白激酶(MAPKs)的抑制剂或磷脂酰肌醇3-激酶(PI3K)抑制剂预处理巨噬细胞,再用脂多糖(LPS)和TREM-1活化抗体刺激,real-time PCR检测IL-1β、MIP-2、TNF-α和IL ...
doaj  

[Tumor-secreted dentin sialophosphoprotein induces oxaliplatin resistance in colorectal cancer through an integrin αvβ3-dependent pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Liu C, Ning Z, Wu J, Liu W, Lin C, Xu J, Zhou R, Zhao L.   +7 more
europepmc   +1 more source

[Research Progress on the Role and Mechanisms of PYCR1 
in Tumorigenesis and Progression]. [PDF]

Zhongguo Fei Ai Za Zhi
Meng Y, Yang Z, Feng H, Li H, Li B.
europepmc   +1 more source

[Research progress on the multidimensional regulation of gut microbiota on metabolism, immunity, and inflammatory response in metabolic associated fatty liver disease]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Wu ST, Lu XL.
europepmc   +1 more source

[Advances on efficacy and mechanisms of acid fibroblast growth factor for promoting injured tissue repair]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Zhu F, Jiang Z, Qian X, Xu Y, Cheng H, Zhang J.   +5 more
europepmc   +1 more source

[Application of Kartogenin in cartilage tissue engineering]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Jiang J, Zhang S, Lu W.
europepmc   +1 more source