Results 181 to 190 of about 736,655 (384)

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source

Supplementary Table 1 from Erlotinib Prolongs Survival in Pancreatic Cancer by Blocking Gemcitabine-Induced MAPK Signals [PDF]

, 2023
Koji Miyabayashi, Hideaki Ijichi, Dai Mohri, Motohisa Tada, Keisuke Yamamoto, Yoshinari Asaoka, Tsuneo Ikenoue, Keisuke Tateishi, Yousuke Nakai, Hiroyuki Isayama, Yasuyuki Morishita, Masao Omata, Harold L. Moses, Kazuhiko Koike   +13 more
openalex   +1 more source

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

Advanced Materials Technologies, EarlyView.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source

ARID1B Gene Deletion Promotes the Proliferation, Migration and Invasion 
of NSCLC Cells

Chinese Journal of Lung Cancer
Background and objective Abnormalities of the switch/sucrose nonfermentable (SWI/SNF) chromatin-remodeling complex are closely related to various cancers, and ARID1B (AT-rich interaction domain 1B) is one of the core subunits of the SWI/SNF complex ...
Linlin ZHU, Xuchao ZHANG
doaj   +1 more source

Ligustroside derived from Ligustrum japonicum inhibits melanogenesis via blocking the MAPK and PKA/CREB signaling pathways

Asian Pacific Journal of Tropical Biomedicine
Objective: To investigate the anti-melanogenic potential of ligustroside isolated from Ligustrum japonicum. Methods: The cytotoxicity of ligustroside was tested via MTT assay.
Xian-Rong Zhou, Fatih Karadeniz, Jung Hwan Oh, Youngwan Seo, Chang-Suk Kong   +4 more
doaj   +1 more source

ERK and p38 MAPK-Activated Protein Kinases: a Family of Protein Kinases with Diverse Biological Functions

Microbiology and Molecular Biology Reviews, 2004
Philippe P Roux, J. Blenis
semanticscholar   +1 more source

Organic Light‐Emitting Diode in Phototherapy Applications

Advanced Photonics Research, EarlyView.
This article systematically reviews the development of organic light‐emitting diodes (OLEDs) in phototherapy, constructs a technical framework, and establishes a multidimensional knowledge graph encompassing indications, wavelengths, and light intensity.
Yingguang Zhu, Yonglan Hu, Yingjie Cui, Lixue Guo, Guohui Zhang, Haixia Qiu, Defu Chen, Changyong Pan, Huijuan Yin, Suling Zhao   +9 more
wiley   +1 more source

Phosphorylation by CK2 and MAPK enhances calnexin association with ribosomes [PDF]

, 1999
Éric Chevet
openalex   +1 more source

MAPK signal pathways in the regulation of cell proliferation in mammalian cells

Cell Research, 2002
Wei Zhang, Hui Liu
semanticscholar   +1 more source

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source