Results 261 to 270 of about 490,180 (313)

METTL11A serves as a novel therapeutic target for acute myeloid leukemia through regulation of the p38-MAPK pathway. [PDF]

Transl Cancer Res
Li J, Zhang J, Zhang P.
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Melatonin alleviates oxidative stress induced damage in human iPSCs harboring mtDNA 3243A>G mutation via MAPK pathway. [PDF]

Stem Cell Res Ther
Pu Z, Wang P, Wang M, Chen Y, Zhu Y, Jiao Y, Zou W, Yu B, Cheng H, Liu Y, Cao Y, Ji D, Liang D.   +12 more
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Jinghuaweikang capsule alleviates <i>Helicobacter pylori</i>-infected gastric mucosal inflammation and drug resistance by regulating intestinal microbiota and MAPK pathway. [PDF]

Front Cell Infect Microbiol
Yang Y, Jia XF, Cui GH, Huang QY, Lin MM, Shi ZM, Ye H, Zhang XZ.   +7 more
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Mating MAPK pathway in Candida albicans

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Compartmentalised MAPK Pathways

2008
The mitogen-activated protein kinase (MAPK) pathway provides cells with the means to interpret external signal cues or conditions, and respond accordingly. This cascade regulates many cell functions such as differentiation, proliferation and migration.
M D, Brown, D B, Sacks
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Pharmacological inhibitors of MAPK pathways

Trends in Pharmacological Sciences, 2002
Mitogen-activated protein kinases [MAPKs, also called extracellular signal-regulated kinases (ERKs)] are constituents of numerous signal transduction pathways, and are activated by protein kinase cascades. Intense efforts are under way to develop and evaluate compounds that target components of MAPK pathways.
Jessie M, English, Melanie H, Cobb
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The MAPK pathway in melanoma

Current Opinion in Oncology, 2008
As understanding of molecular and genetic processes in cancer evolves, so does appreciation of tumor heterogeneity. Tumor profiling has expanded knowledge of relevant pathways, and their interplay. Similar to the revolution in breast cancer with the discovery and successful therapeutic targeting of HER2/neu, the melanoma field is rapidly evolving.
Leslie A, Fecher, Ravi K, Amaravadi, Keith T, Flaherty   +2 more
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Targeting MAPK pathway in melanoma therapy

Cancer and Metastasis Reviews, 2013
New drugs targeting the mitogen-activated protein kinase (MAPK) pathway have generated striking clinical response in melanoma therapy. From the discovery of BRAF mutation in melanoma in 2002, to the approval of first BRAF inhibitor vemurafenib for melanoma treatment by the US Food and Drug Administration in 2011, therapies targeting the MAPK pathway ...
Yabin, Cheng, Guohong, Zhang, Gang, Li
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ERK/MAPK pathway regulates GABAA receptors

Journal of Neurobiology, 2006
The GABAA receptor is a ligand-gated ion channel whose function and activity can be regulated by ligand binding or alternatively may be influenced indirectly through the phosphorylation of specific subunits that comprise the GABAA receptor pentamer. With respect to phosphorylation, most studies have focused on either beta or gamma subunits, whereas the
Cathy L, Bell-Horner, Akiko, Dohi, Quynh, Nguyen, Glenn H, Dillon, Meharvan, Singh   +4 more
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