Results 151 to 160 of about 22,079 (225)

Patient-derived forebrain cortical organoids reveal biphasic tau-MAP6-microtubule axis dysfunction in tauopathy. [PDF]

Alzheimers Dement
Sun X, Ramakrishnan S, Ogbolu VC, Kanaan NM, Karch CM, Baas PW, Qiang L.   +6 more
europepmc   +1 more source

Distinct brain extracellular vesicle microRNA profiles differ in frontotemporal dementia and Alzheimer's disease. [PDF]

Brain Commun
Morgan J, Aarons T, Mukhopadhyay A, Lace G.   +3 more
europepmc   +1 more source

Evaluating MAPT p.A152T as a risk factor for the 3R tauopathy Pick's disease. [PDF]

Brain Commun
Tamvaka N, Scotton W, Lilley MT, Shoai M, Gavrielatos M, Heckman MG, Soto-Beasley AI, Roemer SF, Baker MC, Rademakers R, Murray ME, Dickson DW, Hardy JA, Cook CN, Rohrer JD, Ross OA, Pick’s disease international consortium, Pick’s disease international consortium .   +17 more
europepmc   +1 more source

γ-Radiation induces long-term dose-related proteomic and phosphorylated-tau species changes in non-human primate hippocampus. [PDF]

NPJ Dement
Hatch K, Murphy EK, Olson JD, Cole RN, O'Meally RN, Ingersoll RG, Perl DP, Schaaf GW, Cline JM, Iacono D.   +9 more
europepmc   +1 more source

Tau hyperphosphorylation impairs cooperative binding to microtubules and perturbs organelle trafficking in neurons. [PDF]

Elife
Beaudet D, Berger CL, Hendricks AG.
europepmc   +1 more source

Dendritic translation and neuroproteasome-mediated degradation of endogenous tau revealed by STARFISH. [PDF]

Nat Neurosci
Konrad-Vicario KD, Paradise V, Demir LY, Nguyen C, Makinson CD, Ming Z, Ramachandran KV.   +6 more
europepmc   +1 more source

The Pick fold in tau filaments from human MAPT mutants. [PDF]

Acta Neuropathol
Qi C, Lövestam S, Shi J, Murzin AG, Peak-Chew S, Warner TT, Seelaar H, Cullinane PW, Jaunmuktane Z, van Swieten JC, Scheres SHW, Goedert M.   +11 more
europepmc   +1 more source

Dysregulation of a novel autophagosome-mitochondria contact contributes to tauopathy-related neurodegeneration by disrupting autophagy. [PDF]

Autophagy
Jia N, Zuo Y, Guan H, Rajapaksha G, Cai Q.   +4 more
europepmc   +1 more source

Glymphatic dysfunction, plasma neurofilament light, and cortical free water mediate cognitive decline in familial frontotemporal lobar degeneration. [PDF]

J Prev Alzheimers Dis
Qiu M, Ding L, Bao R, Gong J, Ding W, Shao Z, Han Y, ARTFL-LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) Research Consortium.   +7 more
europepmc   +1 more source

Mutation-specific neuropathologic signatures in MAPT-associated frontotemporal lobar degeneration. [PDF]

Acta Neuropathol
Bogdani M, Jadhav VS, Kraemer BC, Grabowski TJ, Jayadev S, Domoto-Reilly K, Liachko NF, Bird TD, Dirk Keene C, Latimer CS.   +9 more
europepmc   +1 more source