Results 141 to 150 of about 22,079 (225)

Additional file 1 of Different MAPT haplotypes influence expression of total MAPT in postmortem brain tissue

Additional file 1. Table S1: Title: Demographic, clinical and neuropathologic characteristics of individual postmortem brain donors. Description: The LBD Braak stage and AD Braak and Braak stage each consist of six stages. The CERAD score describes neuritic Amyloid-ß plaques in levels of 0, A, B, C. Lewy inclusion pathology assessed semi-quantitatively
Tauber, Christina V., Schwarz, Sigrid C., Rösler, Thomas W., Arzberger, Thomas, Gentleman, Steve, Windl, Otto, Krumbiegel, Mandy, Reis, André, Ruf, Viktoria C., Herms, Jochen, Höglinger, Günter U.   +10 more
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MAPT wt Allele [PDF]

, 2020
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Additional file 2 of Different MAPT haplotypes influence expression of total MAPT in postmortem brain tissue

Additional file 2. Figure S1: Title: α-synuclein pathology in human postmortem brain tissue. Description: Immunohistochemistry for phosphorylated α-synuclein visualizes exemplary Lewy bodies (LB) (arrows) in cortical cell layers of fusiform gyrus of Parkinson (PD) cases but not of control cases of both MAPT haplotypes (H1/H1 and H2/H2). No LB pathology
Tauber, Christina V., Schwarz, Sigrid C., Rösler, Thomas W., Arzberger, Thomas, Gentleman, Steve, Windl, Otto, Krumbiegel, Mandy, Reis, André, Ruf, Viktoria C., Herms, Jochen, Höglinger, Günter U.   +10 more
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Epigenomic of the gene MAPT in tauopathies

, 2016
Les tauopathies sont des maladies neurodégénératives caractérisées par l’agrégation intracérébrale de protéines tau anormales. Cependant ces maladies sont très hétérogènes sur le plan clinique, anatomopathologique mais aussi biochimique avec l'agrégation de différentes isoformes de protéines tau. De nombreux axes de recherche existent à ce jour afin de
openaire   +1 more source

MAPT association with REM sleep behavior disorder [PDF]

Neurology Genetics, 2017
Fernández-Santiago, Rubén, Iranzo, Alex, Gaig, Carles, Serradell, Mónica, Fernández, Manel, Pastor, Pau, Tolosa, Eduardo, Santamaría, Joan, Ezquerra, Mario   +8 more
openaire   +2 more sources

Decoding MAPT Exon 10 Mis-Splicing in FTDP-17: From Pathogenic Mechanisms and Experimental Models to Molecular Therapies. [PDF]

Genes (Basel)
Covello G.
europepmc   +1 more source

Vitamin B6 Modifies Tau-Induced Cellular Stress- and Proteostasis-Related Responses. [PDF]

J Fungi (Basel)
Yılmazer M.
europepmc   +1 more source

"S-Tau-Lled" Lysosomes Disrupt Autophagic Processes in Neurodegeneration. [PDF]

Traffic
Bécot A, Kabani M.
europepmc   +1 more source

NAT10 inhibition corrects nuclear defects in tau mutant human neurons and extends lifespan in a <i>Drosophila</i> tauopathy model. [PDF]

iScience
Paonessa F, Bizzini BD, Campbell T, Coode E, Lam J, Solanki R, Butler R, Smith J, Davidson CM, Larrieu D, Brand AH, Livesey FJ.   +11 more
europepmc   +1 more source

Genetic frontotemporal degeneration across the lifespan? A critical appraisal of the neurodevelopmental hypothesis. [PDF]

Alzheimers Dement
So I, Birkle TJY, Duff KE, Restrepo-Martinez M, Ducharme S, Finger EC.   +5 more
europepmc   +1 more source