Results 111 to 120 of about 33,286 (224)

A surrogate BSL2-compliant infection model recapitulating key aspects of human Marburg virus disease

Emerging Microbes and Infections
Marburg virus disease (MVD) is a severe infectious disease caused by the Marburg virus (MARV), posing a significant threat to humans. MARV needs to be operated under strict biosafety Level 4 (BSL-4) laboratory conditions.
Wanying Yang, Wujie Zhou, Bo Liang, Xiaojun Hu, Shen Wang, Zhenshan Wang, Tiecheng Wang, Xianzhu Xia, Na Feng, Yongkun Zhao, Feihu Yan   +10 more
doaj   +1 more source

Intellectual Property Management Strategies to Accelerate the Development and Access of Vaccines and Diagnostics: Case Studies on Pandemic Influenza, Malaria and SARS [PDF]

, 2006
Achieving global access to vaccines, diagnostics, and pharmaceuticals remains a challenge. Throughout the developing world, intellectual property (IP) constraints complicate access to critically essential medical technologies and products.
Eiss, Robert, Kowalski, Stanley P., Krattiger, Anatole, Taubman, Anthony   +3 more
core   +1 more source

Ebola : too far or so close? [PDF]

, 2014
The year 2014 has witnessed the escalation of the largest ever Ebola outbreak which started in Guinea, and later spread to other countries in West Africa.
Pace, David, Torpiano, Paul
core  

Transcriptomics of Marburg virus-infected primary proximal tubular cells reveals negative correlation of immune response and energy metabolism

Virus Research
Marburg virus, a member of the Filoviridae, is the causative agent of Marburg virus disease (MVD), a hemorrhagic fever with a case fatality rate of up to 90 %.
Benjamin Koch, Maximilian Filzmayer, Sammy Patyna, Nils Wetzstein, Sebastian Lampe, Tobias Schmid, Helmut Geiger, Patrick C. Baer, Olga Dolnik   +8 more
doaj   +1 more source

Lessons from the outbreak of Marburg virus. [PDF]

, 2005
Borchert, Matthias, Mulangu, Sabue, Van der Stuyft, Patrick   +2 more
core   +1 more source

Some Remarks about the Complexity of Epidemics Management

, 2017
Recent outbreaks of Ebola, H1N1 and other infectious diseases have shown that the assumptions underlying the established theory of epidemics management are too idealistic. For an improvement of procedures and organizations involved in fighting epidemics,
Brown, André EX, Ch'ng, Quee-Lim, Currie, Michael, Grundy, Laura J, Hokanson, Jim, Javer, Avelino, Kerr, Rex, Lee, Chee Wai, Li, Chris, Li, Kezhi, Schafer, William R, Yemini, Eviatar   +11 more
core   +4 more sources

How Rwanda mounted a research response with an investigational vaccine just ten days into a Marburg outbreak

npj Vaccines
The September 2024 outbreak of Marburg virus disease (MVD) represented the first time this virus was identified in Rwanda. Health authorities mounted a rapid and effective response, including the rapid execution of an open-label Phase 2 clinical trial of
Sabin Nsanzimana, Noella Bigirimana, Richard Hatchett, Sue Bailey, Natacha Butera, Yvan Butera, Jakob P. Cramer, Amy Finan, Caroline M. Forkin, Adam M. Hacker, Sibomana Hassan, Vicky Leamy, Vincent Mutabazi, Julien Nyombayire, Eric Remera, Edson Rwagasore, Eduardo Tedeschi, Kelly L. Warfield, Nicole Lurie   +18 more
doaj   +1 more source

Evaluation of long-term immunity following inoculation with highly diverse orthomarburgvirus isolates in Egyptian rousette bats (Rousettus aegyptiacus)

Journal of Virology
Viral coinfections and their impact on long-term immunity represent an understudied area in disease ecology and infectious disease research. Coinfections can influence the host’s susceptibility to future infections, alter host and pathogen population ...
Jessica A. Elbert, Amy J. Schuh, Brian R. Amman, Jonathan C. Guito, James C. Graziano, Tara K. Sealy, Elizabeth W. Howerth, Jonathan S. Towner   +7 more
doaj   +1 more source

Enhancing Global Health Security in Sub-Saharan Africa: The case for integrated One Health surveillance against zoonotic diseases and environmental threats

One Health
Integrated One Health surveillance is pivotal to Africa's future health security, particularly in preventing and managing zoonotic and environmental health threats.
Pierre Gashema, Placide Sesonga, Patrick Gad Iradukunda, Richard Muvunyi, Jean Claude Mugisha, Jerome Ndayisenga, Tumusime Musafiri, Richard Habimana, Radjabu Bigirimana, Alice Kabanda, Misbah Gashegu, Noel Gahamanyi, Jonathan Izudi, Emmanuel Edwar Siddig, Jean Claude Semuto Ngabonziza, Ayman Ahmed, Tafadzwa Dzinamarira, Leon Mutesa, Claude Mambo Muvunyi   +18 more
doaj   +1 more source

Non-Ebola Filoviruses: Potential Threats to Global Health Security

Viruses
Filoviruses are negative-sense single-stranded RNA viruses often associated with severe and highly lethal hemorrhagic fever in humans and nonhuman primates, with case fatality rates as high as 90%.
Yannick Munyeku-Bazitama, Francois Edidi-Atani, Ayato Takada   +2 more
doaj   +1 more source