Results 101 to 110 of about 33,286 (224)

Experimental Vaccines for Prevention of Marburg Hemorrhagic Fever and Animal Models for Studying Pathogenesis

Проблемы особо опасных инфекций, 2018
Marburg fever is an acute natural-focal disease characterized by severe course, hemorrhagic syndrome, high level of contagiousness and lethality. The causative agent of the disease is the RNA-containing virus belonging to the family of filoviruses ...
N. V. Volkova, E. I. Kazachinskaya, D. N. Shcherbakov   +2 more
doaj   +1 more source

Energy-filtered transmission electron microscopy of biological samples on highly transparent carbon nanomembranes

, 2011
Ultrathin carbon nanomembranes (CNM) comprising crosslinked biphenyl precursors have been tested as support films for energy-filtered transmission electron microscopy (EFTEM) of biological specimens.
Beyer, André, Büenfeld, Matthias, Gölzhäuser, Armin, Hampp, Norbert, Kühlbrandt, Werner, Rhinow, Daniel, Turchanin, Andrey, Weber, Nils-Eike   +7 more
core   +1 more source

Drivers of disease emergence and spread: Is wildlife to blame? [PDF]

, 2014
The global focus on wildlife as a major contributor to emerging pathogens and infectious diseases (EIDs) in humans and domestic animals is not based on field, experimental or dedicated research, but mostly on limited surveys of literature, opinion and ...
Kock, R A
core   +2 more sources

An economic analysis of a pneumococcal vaccine programme in people aged over 64 years in a developed country setting. [PDF]

, 2005
BACKGROUND: Polysaccharide pneumococcal vaccination for older adults is being introduced in developed country settings. Evidence of protection by this vaccine against pneumococcal pneumonia, or confirmation that illness and death from bacteraemia are ...
Cutts, Felicity T, Hall, Andrew J, Mangtani, Punam, Roberts, Jennifer A   +3 more
core   +1 more source

Ebola research funding: a systematic analysis, 1997–2015

, 2016
Background: The latest outbreak of Ebola in West Africa overwhelmed the affected countries, with the impact on health extending far beyond Ebola–related deaths that have exceeded 11?000.
Atun, Rifat, Fitchett, Joseph R.A., Head, Michael, Lichtman, Amos, Low, Ariel, Soyode, Damilola T., Villar de Onis, Jimena   +6 more
core   +1 more source

Interactions of Marburg Virus Nucleocapsid Proteins

Virology, 1998
In this study, the components of Marburg virus nucleocapsid complex were determined, and interactions between the compounds were investigated. Using salt dissociation of isolated virions, four proteins (NP, VP35, VP30, and L) remained attached to the core complex.
Becker, S., Rinne, C., Hofsäß, U., Klenk, H.-D., Mühlberger, E.   +4 more
openaire   +2 more sources

Potent immunogenicity and protective efficacy of a multi-pathogen vaccination targeting Ebola, Sudan, Marburg and Lassa viruse.

PLoS Pathogens
Viral haemorrhagic fevers (VHF) pose a significant threat to human health. In recent years, VHF outbreaks caused by Ebola, Marburg and Lassa viruses have caused substantial morbidity and mortality in West and Central Africa.
Amy Flaxman, Sarah Sebastian, Sofia Appelberg, Kuan M Cha, Marta Ulaszewska, Jyothi Purushotham, Ciaran Gilbride, Hannah Sharpe, Alexandra J Spencer, Sagida Bibi, Daniel Wright, Isabel Schmidt, Stuart Dowall, Linda Easterbrook, Stephen Findlay-Wilson, Sarah Gilbert, Ali Mirazimi, Teresa Lambe   +17 more
doaj   +1 more source

Establishment of pseudovirus infection mouse models for in vivo pharmacodynamics evaluation of filovirus entry inhibitors

Acta Pharmaceutica Sinica B, 2018
Filoviruses cause severe and fatal viral hemorrhagic fever in humans. Filovirus research has been extensive since the 2014 Ebola outbreak. Due to their high pathogenicity and mortality, live filoviruses require Biosafety Level-4 (BSL-4) facilities, which
Qing Chen, Ke Tang, Xiaoyu Zhang, Panpan Chen, Ying Guo   +4 more
doaj   +1 more source

Experimental Inoculation of Egyptian Rousette Bats (Rousettus aegyptiacus) with Viruses of the Ebolavirus and Marburgvirus Genera

Viruses, 2015
The Egyptian rousette bat (Rousettus aegyptiacus) is a natural reservoir for marburgviruses and a consistent source of virus spillover to humans. Cumulative evidence suggests various bat species may also transmit ebolaviruses.
Megan E.B. Jones, Amy J. Schuh, Brian R. Amman, Tara K. Sealy, Sherif R. Zaki, Stuart T. Nichol, Jonathan S. Towner   +6 more
doaj   +1 more source

Persistence and Organ Tropism of Filoviruses in Farmed European Perch (Perca fluviatilis)

Journal of Fish Diseases, Volume 49, Issue 5, May 2026.
Johanna Perschthaler, Nicole Wildi, Lena K. Matthiss, Torsten Seuberlich, Heike Schmidt‐Posthaus   +4 more
wiley   +1 more source