Carbohydrate structure of Marburg virus glycoprotein [PDF]
Marburg virus was propagated in E6 cells, a cloned cell line of Vero cells, in the presence of [6-3H]glucosamine. Radiolabelled viral glycoprotein was digested with trypsin, and oligosaccharides were liberated by sequential treatment with endo-beta-N-acetylglucosaminidase H, peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase F and O-glycosidase,
H, Geyer +4 more
openaire +2 more sources
Public Health Achievements in Rwanda: A 21st Century Transformation
This narrative review examines Rwanda's post‐2000 public health transformation using the WHO health system building blocks. It shows how strategic governance, universal health coverage via mutuelle de santé, community health workers, and digital health tools have driven substantial gains in maternal/child health, infectious disease control, and ...
Niyibizi Julius +2 more
wiley +1 more source
High awareness of viral outbreaks in Dar es Salaam coexists with critical knowledge gaps, stigma, and vaccine hesitancy driven by trust and safety concerns. Targeted myth correction, anti‐stigma initiatives, and strategic digital health communication are essential to strengthen community preparedness and outbreak response.
Mohammed Elmogiera Fadlallh Elsayed +2 more
wiley +1 more source
Molecular identification of adenoviruses associated with respiratory infection in Egypt from 2003 to 2010. [PDF]
BACKGROUND: Human adenoviruses of species B, C, and E (HAdV-B, -C, -E) are frequent causative agents of acute respiratory infections worldwide. As part of a surveillance program aimed at identifying the etiology of influenza-like illness (ILI) in Egypt ...
A Kandeel +57 more
core +1 more source
Infectious Disease Response in Tanzania: Enhanced Strategies From the 2023 to 2025 Marburg Outbreaks
ABSTRACT The 2023 Marburg virus disease (MVD) outbreak in Tanzania, which resulted in nine confirmed cases and six deaths (case fatality rate [CFR]: 66.7%), served as a critical stress test of the national health system, revealing significant gaps in outbreak preparedness across surveillance, laboratory capacity, and infection prevention and control ...
Huda Haque +6 more
wiley +1 more source
The Ebola virus disease outbreak in Tonkolili district, Sierra Leone: a retrospective analysis of the Viral Haemorrhagic Fever surveillance system, July 2014–June 2015 [PDF]
In Sierra Leone, the Ebola virus disease (EVD) outbreak occurred with substantial differences between districts with someone even not affected. To monitor the epidemic, a community event-based surveillance system was set up, collecting data into the ...
Colizzi, Vittorio +7 more
core +1 more source
ABSTRACT HeLa cells expressing the recombinant Marburg virus (MBGV) nucleoprotein (NP) have been studied by immunoelectron microscopy. It was found that MBGV NPs assembled into large aggregates which were in close association with membranes of the rough endoplasmic reticulum.
L, Kolesnikova +3 more
openaire +3 more sources
Experimental Success in Marburg Virus Vaccination
The Marburg virus (MRV), classified within the Filoviridae family, was initially identified in 1967, precipitating Marburg virus disease (MARV), a severe and often fatal hemorrhagic fever.
Martyna Dydyk, Aleksandra Nowak
doaj +1 more source
Studies of Reservoir Hosts for Marburg Virus
To determine reservoir hosts for Marburg virus (MARV), we examined the fauna of a mine in northeastern Democratic Republic of the Congo. The mine was associated with a protracted outbreak of Marburg hemorrhagic fever during 1998–2000.
Robert Swanepoel +17 more
doaj +1 more source
Lyophilisation of lentiviral pseudotypes for the development and distribution of virus neutralisation assay kits for rabies, Marburg and influenza viruses [PDF]
Purpose: Some conventional serological assays can accurately quantify neutralising antibody responses raised against epitopes on virus glycoproteins, enabling mass vaccine evaluation and serosurveillance studies to take place. However, these assays often
Mather, Stuart +3 more
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