Results 71 to 80 of about 15,535 (172)

The Problematic Diseases of viral Hemorrhagic Fever: Insights into Ebola, Marburg, and Dengue Fever Viruses [PDF]

ERU Research Journal
Viral Hemorrhagic Fever Diseases are critical health problems worldwide. Several outbreaks of hemorrhagic fever diseases have emerged in the last few years in different countries, particularly in tropical and subtropical regions of Africa, raising ...
Tharwat El-khamissy, Mohammed Abdo
doaj   +1 more source

Experimental Vaccines for Prevention of Marburg Hemorrhagic Fever and Animal Models for Studying Pathogenesis

Проблемы особо опасных инфекций, 2018
Marburg fever is an acute natural-focal disease characterized by severe course, hemorrhagic syndrome, high level of contagiousness and lethality. The causative agent of the disease is the RNA-containing virus belonging to the family of filoviruses ...
N. V. Volkova, E. I. Kazachinskaya, D. N. Shcherbakov   +2 more
doaj   +1 more source

Potent immunogenicity and protective efficacy of a multi-pathogen vaccination targeting Ebola, Sudan, Marburg and Lassa viruse.

PLoS Pathogens
Viral haemorrhagic fevers (VHF) pose a significant threat to human health. In recent years, VHF outbreaks caused by Ebola, Marburg and Lassa viruses have caused substantial morbidity and mortality in West and Central Africa.
Amy Flaxman, Sarah Sebastian, Sofia Appelberg, Kuan M Cha, Marta Ulaszewska, Jyothi Purushotham, Ciaran Gilbride, Hannah Sharpe, Alexandra J Spencer, Sagida Bibi, Daniel Wright, Isabel Schmidt, Stuart Dowall, Linda Easterbrook, Stephen Findlay-Wilson, Sarah Gilbert, Ali Mirazimi, Teresa Lambe   +17 more
doaj   +1 more source

Rwanda’s lessons for strengthening Africa’s response to current Marburg virus disease outbreaks

The Lancet Global Health
Summary: Marburg virus disease remains a major threat to global health security in Africa, where recurrent filovirus outbreaks intersect with fragile health systems.
Claude Mambo Muvunyi, Prof, Pierre Gashema, MSc, Eric Seruyange, PhD, ProfPhD Theogene Twagirumugabe, PhD, Isabelle Mukagatare, MD, Patrick Gad Iradukunda, MSc, Radjabu Bigirimana, MD, Emmanuel Edwar Siddig, PhD, Edson Rwagasore, MD, Jean de Dieu Harelimana, PhD, ProfPhD Sanctus Musafiri, PhD   +10 more
doaj   +1 more source

A surrogate BSL2-compliant infection model recapitulating key aspects of human Marburg virus disease

Emerging Microbes and Infections
Marburg virus disease (MVD) is a severe infectious disease caused by the Marburg virus (MARV), posing a significant threat to humans. MARV needs to be operated under strict biosafety Level 4 (BSL-4) laboratory conditions.
Wanying Yang, Wujie Zhou, Bo Liang, Xiaojun Hu, Shen Wang, Zhenshan Wang, Tiecheng Wang, Xianzhu Xia, Na Feng, Yongkun Zhao, Feihu Yan   +10 more
doaj   +1 more source

Transcriptomics of Marburg virus-infected primary proximal tubular cells reveals negative correlation of immune response and energy metabolism

Virus Research
Marburg virus, a member of the Filoviridae, is the causative agent of Marburg virus disease (MVD), a hemorrhagic fever with a case fatality rate of up to 90 %.
Benjamin Koch, Maximilian Filzmayer, Sammy Patyna, Nils Wetzstein, Sebastian Lampe, Tobias Schmid, Helmut Geiger, Patrick C. Baer, Olga Dolnik   +8 more
doaj   +1 more source

Issue Information

Environmental Microbiology Reports, Volume 18, Issue 4, August 2026.
wiley   +1 more source

How Rwanda mounted a research response with an investigational vaccine just ten days into a Marburg outbreak

npj Vaccines
The September 2024 outbreak of Marburg virus disease (MVD) represented the first time this virus was identified in Rwanda. Health authorities mounted a rapid and effective response, including the rapid execution of an open-label Phase 2 clinical trial of
Sabin Nsanzimana, Noella Bigirimana, Richard Hatchett, Sue Bailey, Natacha Butera, Yvan Butera, Jakob P. Cramer, Amy Finan, Caroline M. Forkin, Adam M. Hacker, Sibomana Hassan, Vicky Leamy, Vincent Mutabazi, Julien Nyombayire, Eric Remera, Edson Rwagasore, Eduardo Tedeschi, Kelly L. Warfield, Nicole Lurie   +18 more
doaj   +1 more source

Evaluation of long-term immunity following inoculation with highly diverse orthomarburgvirus isolates in Egyptian rousette bats (Rousettus aegyptiacus)

Journal of Virology
Viral coinfections and their impact on long-term immunity represent an understudied area in disease ecology and infectious disease research. Coinfections can influence the host’s susceptibility to future infections, alter host and pathogen population ...
Jessica A. Elbert, Amy J. Schuh, Brian R. Amman, Jonathan C. Guito, James C. Graziano, Tara K. Sealy, Elizabeth W. Howerth, Jonathan S. Towner   +7 more
doaj   +1 more source

Determinants of healthcare workers’ attitudes towards Marburg virus disease outbreak response in Northwest Ethiopia: a cross-sectional study

BMC Public Health
Background Healthcare workers’ professional attitudes are critical for effective outbreak response. Understanding the drivers of these attitudes is essential for strengthening epidemic resilience, particularly for high-threat pathogens like the Marburg ...
Melaku Laikemariam, Endalamaw Fentie, Abebe Yenesew   +2 more
doaj   +1 more source