Results 71 to 80 of about 1,176,948 (213)

Ultrastructural Organization of Recombinant Marburg Virus Nucleoprotein: Comparison with Marburg Virus Inclusions

Journal of Virology, 2000
ABSTRACT HeLa cells expressing the recombinant Marburg virus (MBGV) nucleoprotein (NP) have been studied by immunoelectron microscopy. It was found that MBGV NPs assembled into large aggregates which were in close association with membranes of the rough endoplasmic reticulum.
L, Kolesnikova, E, Mühlberger, E, Ryabchikova, S, Becker   +3 more
openaire   +3 more sources

Identification of CCZ1 as an essential lysosomal trafficking regulator in Marburg and Ebola virus infections

Nature Communications, 2023
Marburg and Ebola filoviruses are two of the deadliest infectious agents and several outbreaks have occurred in the last decades. Although several receptors and co-receptors have been reported for Ebola virus, key host factors remain to be elucidated. In
Vanessa Monteil, Hyesoo Kwon, Lijo John, Cristiano Salata, Gustav Jonsson, Sabine U. Vorrink, Sofia Appelberg, Sonia Youhanna, Matheus Dyczynski, Alexandra Leopoldi, Nicole Leeb, Jennifer Volz, Astrid Hagelkruys, Max J. Kellner, Stéphanie Devignot, Georg Michlits, Michelle Foong-Sobis, Friedemann Weber, Volker M. Lauschke, Moritz Horn, Heinz Feldmann, Ulrich Elling, Josef M. Penninger, Ali Mirazimi   +23 more
doaj   +1 more source

Obtaining Recombinant Antigens for the Development of Serological Diagnosis of Marburg Fever

Проблемы особо опасных инфекций, 2021
Aim. Production of recombinant viral antigens of the main immunodominant proteins: glycoprotein (GPΔMLD), nucleoprotein (NP) and matrix protein (VP40) of the Marburg virus, as well as the study of their antigenic and immunogenic properties.Materials and ...
N. V. Volkova, A. V. Ivanova, A. A. Isaeva, O. A. Polezhaeva, A. V. Zaykovskaya, D. N. Shcherbakov, E. I. Kazachinskaya   +6 more
doaj   +1 more source

Kcnv2 E151X Mouse Captures Hallmarks of KCNV2‐Associated Retinal Dystrophy

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background KCNV2‐associated retinopathy is a rare inherited retinal dystrophy caused by variants in the KCNV2 gene, leading to disrupted photoreceptor behaviour and progressive deterioration of vision. Patients have characteristic electroretinography abnormalities, including reduced cone response, delayed and reduced rod response to low light ...
Nermina Xhaferri, Sumit Biswas, Benjamin Davies, Moritz Lindner   +3 more
wiley   +1 more source

Vorlesungen / Philipps-Universität Marburg. Im Winterhalbjahr 1929/30.

, 2020
Elektronische Reproduktion von: Vorlesungen / Philipps-Universität Marburg. Im Winterhalbjahr 1929/30.. - Standort: Universität Marburg, Universitätsbibliothek. - Signatur: VIII C 1169. - Bemerkungen: (Hassiaca).
Philipps-Universität Marburg
core   +1 more source

Preimaginal development of Aedes aegypti L. (Diptera: Culicidae) in brackish water gives rise to adult mosquitoes with thicker cuticles and greater insecticide resistance

Medical and Veterinary Entomology, EarlyView.
The principal arboviral vector Aedes aegypti can develop in coastal brackish water field habitats (0.5–15 g/L salt) with larvae possessing thicker cuticles and greater resistance to the larvicide Temephos. Females emerging from brackish water‐developing preimaginal stages are now shown to have thicker and remodelled leg and abdominal cuticles and ...
Kokila Sivabalakrishnan, Andrew Hemphill, S. H. P. Parakrama Karunaratne, Arunasalam Naguleswaran, Isabel Roditi, Sinnathamby N. Surendran, Ranjan Ramasamy   +6 more
wiley   +1 more source

Marburg Virus in Fruit Bat, Kenya

Emerging Infectious Diseases, 2010
(Uploaded by Plazi for the Bat Literature Project) No abstract provided.
Kuzmin, Ivan V., Niezgoda, Michael, Franka, Richard, Agwanda, Bernard, Markotter, Wanda, Breiman, Robert F., Shieh, Wun-Ju, Zaki, Sherif R., Rupprecht, Charles Edward   +8 more
openaire   +5 more sources

The Current Pathogenicity and Potential Risk Evaluation of Marburg Virus to Cause Mysterious “Disease X”—An Update on Recent Evidences

Environmental Health Insights
The World Health Organization (WHO) defined Disease X as an upcoming disease with the potential to cause a pandemic. Pathogen X is responsible for Disease X.
Rahima Akter Mitu, Md. Rabiul Islam
doaj   +1 more source

Cell wall integrity and elicitor peptide signaling modulate jasmonic acid‐mediated camalexin production in Arabidopsis

New Phytologist, EarlyView.
Model of the cell wall damage (CWD)‐responsive signaling network leading to camalexin biosynthesis. Summary Plant cell walls constitute dynamic barriers that are essential for defense against pathogens. Beyond a structural role in blocking pathogen infection, innate mechanisms monitor cell wall integrity (CWI) in Arabidopsis thaliana and trigger local ...
Richard Noi Morton, Lian Fleischberger, Joy Debnath, David Biermann, Susanne Mühlbauer, Ahalya Rajendran, Hans‐Henning Kunz, Julien Gronnier, Nora Gigli Bisceglia, Timo Engelsdorf   +9 more
wiley   +1 more source

In silico exploration of deep-sea fungal metabolites as inhibitor of Ebola and Marburg VP35 and VP40.

PLoS ONE
VP30 and VP40 proteins of Ebola and Marburg viruses have been recognized as potential targets for antiviral drug development due to their essential roles in the viral lifecycle.
Abdullah R Alanzi, Mohammed F Alajmi, Mohammed S Al-Dosari, Mohammad K Parvez, Moneerah J Alqahtani   +4 more
doaj   +1 more source