Results 61 to 70 of about 1,176,948 (213)
Isolated Case of Marburg Virus Disease, Kampala, Uganda, 2014
Emerging Infectious Diseases, 2017 In September 2014, a single fatal case of Marburg virus was identified in a healthcare worker in Kampala, Uganda. The source of infection was not identified, and no secondary cases were identified.
Luke Nyakarahuka +15 more
doaj +1 more source
Safety and pharmacokinetics of inhaled aloxistatin: A first‐in‐human phase 1 dose escalation trial
British Journal of Clinical Pharmacology, EarlyView.Aims Aloxistatin (E64d) is a membrane‐permeable cysteine protease inhibitor prodrug that is converted by esterases to the active metabolite E64c (loxistatin). This first‐in‐human study evaluated the safety, tolerability and pharmacokinetics of single ascending doses of inhaled E64d in healthy volunteers.
Sebastian Fähndrich +24 more
wiley +1 more source
Ebola and Marburg virus matrix layers are locally ordered assemblies of VP40 dimers
eLife, 2020 Filoviruses such as Ebola and Marburg virus bud from the host membrane as enveloped virions. This process is achieved by the matrix protein VP40. When expressed alone, VP40 induces budding of filamentous virus-like particles, suggesting that localization
William Wan +8 more
doaj +1 more source
Everyone Knows It's a Hoax: The Role of Perceived Descriptive Norms in Conspiracy Beliefs
European Journal of Social Psychology, EarlyView.ABSTRACT People's belief in conspiracy theories is shaped by social influence processes. This contribution investigated these processes in six studies (total N = 2906) by examining the role of descriptive norms, that is, the perception that others endorse conspiracy theories.
Jan‐Willem van Prooijen +3 more
wiley +1 more source
Allergy, EarlyView.ABSTRACT Allergen immunotherapy (AIT) has been acknowledged as the only disease‐modifying treatment for respiratory diseases since its introduction in 1911. Although the efficacy and safety have convincingly been established in numerous randomized clinical trials (RCTs), the AIT study results may vary substantially.
Roy Gerth van Wijk +10 more
wiley +1 more source
The nucleoprotein of Marburg virus is phosphorylated
Journal of General Virology, 1994 The nucleoprotein (NP) of Marburg virus (MBG), a filovirus, is encoded by the gene closest to the 3' end of the non-segmented negative-strand RNA genome. Sequence comparison has indicated that NP is the functional equivalent to the nucleoproteins of paramyxoviruses and rhabdoviruses. Expression of recombinant NP in two eukaryotic systems using vaccinia
S, Becker +3 more
openaire +2 more sources
Kreisblatt für die Kreise Marburg und Kirchhain. Jg. 1914
, 2014 Layoutgetreues Digitalisat der Ausg.: Marburg : Koch, 1914 Standort: Universitätsbibliothek Marburg, Zentralbibliothek (000) Signatur: VIII A 1804, Beil.
Landkreis Marburg
core +1 more source
Vorlesungsverzeichnis der Philosophischen Fakultät / Philipps-Universität Marburg. WS 1945/46.
, 2020 Elektronische Reproduktion von: Vorlesungsverzeichnis der Philosophischen Fakultät / Philipps-Universität Marburg. WS 1945/46. - Standort: Universität Marburg, Universitätsbibliothek. - Signatur: VIII C 1169.
Philipps-Universität Marburg
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Andrology, EarlyView.ABSTRACT Testicular germ cell tumors (TGCT) are the leading malignancy in adolescent and young adult males, yet the immunological and cellular mechanisms governing their tumor microenvironment (TME) remain poorly understood. Here, we present a comprehensive review of TGCT pathobiology with a focus on the immune landscape, particularly the role of tumor‐
R Islam +7 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Aldosterone plays a key role in blood pressure and volume regulation. Enhanced aldosterone secretion contributes to cardiovascular and renal diseases. Therefore, inhibitors of aldosterone receptors and synthase are essential drugs for the treatment of hypertension and heart failure.
Sanika Mohagaonkar +6 more
wiley +1 more source