Results 51 to 60 of about 33,286 (224)

Expansion of neopterin and beta2-microglobulin in cerebrospinal fluid reaches maximum levels early and late in the course of human immunodeficiency virus infection [PDF]

, 1992
Inhaltsverzeichnis ...
Bogner, Johannes R., Goebel, Frank-Detlef, Junge-Hülsing, B., Kronawitter, Ursula, Matuschke, A., Sadri, Ifna   +5 more
core   +1 more source

On‐deck pH measurement with integrated feedback control on a micro‐scale platform for monoclonal antibody low pH viral inactivation

Biotechnology Progress, EarlyView.
Integrating an automated, on‐deck pH measurement method with feedback control enables precise, real‐time pH adjustment during low pH viral inactivation on a micro‐scale platform. Abstract The increasing demand for efficient monoclonal antibody manufacturing has accelerated the adoption of high throughput process development (HTPD) platforms, which ...
Paras Sharma, Nikolas von den Eichen, Sabine Schweisgut, Lars Robbel, Michael Schmitt, Daniel G. Bracewell   +5 more
wiley   +1 more source

Outbreak of Marburg hemorrhagic fever among miners in Kamwenge and Ibanda Districts, Uganda, 2007 [PDF]

, 2011
Marburg hemorrhagic fever was detected among 4 miners in Ibanda District, Uganda, from June through September, 2007. Infection was likely acquired through exposure to bats or bat secretions in a mine in Kamwenge District, Uganda, and possibly human-to ...
Atek Kagirita, Bausch, Bausch, Ben Jeffs, Brian Amman, Centers for Disease Control and Prevention, Centers for Disease Control and Prevention, Craig Manning, Edgar Kansiime, Eileen C. Farnon, Emmanuel Byaruhanga, F. Katunguka, Florimond Tschioko, Godfrey S. Bwire, Jennifer Adjemian, Jentes, Jonathan Towner, Jordan W. Tappero, Joseph F. Wamala, Julius J. Lutwama, Pierre E. Rollin, Pierre Formenty, Robert Downing, Sam Ahimbisibwe, Stuart T. Nichol, Swanepoel, Taylor, Timen, Towner, Towner, Wahl-Jensen, World Health Organization   +31 more
core   +2 more sources

Marburg virus-like particles protect guinea pigs from lethal Marburg virus infection [PDF]

Vaccine, 2004
Ongoing outbreaks of filoviruses in Africa and concerns about their use in bioterrorism attacks have led to intense efforts to find safe and effective vaccines to prevent the high mortality associated with these viruses. We previously reported the generation of virus-like particles (VLPs) for the filoviruses, Marburg (MARV) and Ebola (EBOV) virus, and ...
Kelly L, Warfield, Dana L, Swenson, Diane L, Negley, Alan L, Schmaljohn, M Javad, Aman, Sina, Bavari   +5 more
openaire   +2 more sources

ProTides for Antiviral Activity Beyond Liver Cells

Chemistry – A European Journal, EarlyView.
A strategy for obtaining prodrugs of antiviral nucleotides with broad tissue activity is presented that relies on cycloalkyl or cycloalkylalkyl esters, improving uptake and esterase cleavage, and producing nanomolar inhibitors in kidney, colon, and lung cells.
Felix Goebel, Adrian Humboldt, Heeyoung Kim, Carl J. M. Schölzel, Ralf Bartenschlager, Clemens Richert   +5 more
wiley   +1 more source

Identification of CCZ1 as an essential lysosomal trafficking regulator in Marburg and Ebola virus infections

Nature Communications, 2023
Marburg and Ebola filoviruses are two of the deadliest infectious agents and several outbreaks have occurred in the last decades. Although several receptors and co-receptors have been reported for Ebola virus, key host factors remain to be elucidated. In
Vanessa Monteil, Hyesoo Kwon, Lijo John, Cristiano Salata, Gustav Jonsson, Sabine U. Vorrink, Sofia Appelberg, Sonia Youhanna, Matheus Dyczynski, Alexandra Leopoldi, Nicole Leeb, Jennifer Volz, Astrid Hagelkruys, Max J. Kellner, Stéphanie Devignot, Georg Michlits, Michelle Foong-Sobis, Friedemann Weber, Volker M. Lauschke, Moritz Horn, Heinz Feldmann, Ulrich Elling, Josef M. Penninger, Ali Mirazimi   +23 more
doaj   +1 more source

Presence and persistence of Ebola or Marburg virus in patients and survivors: A rapid systematic review [PDF]

, 2016
Background: The 2013-15 Ebola outbreak was unprecedented due to sustainedtransmission within urban environments and thousands of survivors. In 2014 the World Health Organization stated that there was insufficient evidence to give definitive guidance ...
Brainard, Julii, Edmunds, Kelly, Hooper, Lee, Hunter, Paul, Pond, Katherine   +4 more
core   +3 more sources

Engaging the public in plant science: Communication facilitators and barriers of scaling up a citizen science campaign

People and Nature, EarlyView.
Abstract Volunteers have been involved in nature observations for decades through citizen science initiatives, providing large data sets as well as problem identification that allow a more complete understanding of many natural phenomena. Although communication is a core component in citizen science, the key factors that determine its effectiveness in ...
Kristiina Gibson, Monika Suškevičs, Baiba Prūse, Marta Barberis, Sara A. O. Cousins, Živa Fišer, Margaux Julien, Marianne Kivastik, Marcin Klisz, Attila Lengyel, Zuzana Münzbergová, Radosław Puchałka, Iris Reinula, Froukje Rienks, Julie Koch Sheard, Viktor Siverin, Bojana Stojanova, Sabrina Träger, Tsipe Aavik   +18 more
wiley   +1 more source

Regional Initiatives in Support of Surveillance in East Africa: The East Africa Integrated Disease Surveillance Network (EAIDSNet) Experience. [PDF]

, 2013
The East African Integrated Disease Surveillance Network (EAIDSNet) was formed in response to a growing frequency of cross-border malaria outbreaks in the 1990s and a growing recognition that fragmented disease interventions, coupled with weak laboratory
Bond KC, Gresham L, James Kariuki, Leonard E.G Mboera, Maurice Ope, Mayala BK, Mboera LEG, Miriam Schneidman, Mwihaki Kimura, Olago D, Ramana N.V Gandham, Shikanga O, Stanley Sonoiya, WHO, WHO   +14 more
core   +1 more source

Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report

Allergy, EarlyView.
ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter, Ioana Agache, Beatriz Cabanillas, Roberto Berni Canani, Pasquale Comberiati, Holger Garn, Cristina Gomez‐Casado, Karin Hufnagl, Ekaterina Khaleva, Gregorio P. Milani, Daniel Munblit, Nikolaos Douladiris, Liam O'Mahony, Frank Redegeld, Carmen Riggioni, Peter K. Smith, Betty van Esch, Emilia Vassilopoulou, Carina Venter, Diego G. Peroni   +19 more
wiley   +1 more source