Results 21 to 30 of about 1,110,298 (219)

Structural insight into Marburg virus nucleoprotein–RNA complex formation

Nature Communications, 2022
Marburg virus causes severe hemorrhagic fever in humans. Here, the authors determine the structure of Marburg virus nucleoprotein–RNA complex by cryo-electron microscopy and provide mechanistic insight into the helical assembly of the nucleocapsid.
Yoko Fujita-Fujiharu, Yukihiko Sugita, Yuki Takamatsu, Kazuya Houri, Manabu Igarashi, Yukiko Muramoto, Masahiro Nakano, Yugo Tsunoda, Ichiro Taniguchi, Stephan Becker, Takeshi Noda   +10 more
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Forty Years of Marburg Virus [PDF]

The Journal of Infectious Diseases, 2007
Forty years ago, in early August 1967, the first filovirus ever detected, Marburg virus, made its appearance in Europe, causing severe and often fatal hemorrhagic fever in laboratory workers in Marburg and Frankfurt and, about 4 weeks later, in Belgrade. The etiological agent was isolated and identified by the combined efforts of virologists in Marburg
Werner, Slenczka, Hans Dieter, Klenk
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Immunogenic and Protective Features of the Recombinant Vaccinia Virus Strain Expressing Cassette of Genes of Marburg Virus Structural Proteins

Проблемы особо опасных инфекций, 2022
The aim of the study was to create a highly immunogenic vaccine construct based on a recombinant variant of a replication-defective MVA strain of vaccinia virus, expressing virus-like particles that mimic natural infection with Marburg virus.
A. V. Semenova, G. F. Sivolobova, A. A. Grazhdantseva, S. A. P’yankov, I. S. Shul’gina, O. S. Taranov, O. V. P’yankov, D. V. Antonets, L. I. Karpenko, E. V. Starostina, M. V. Borgoyakova, A. N. Chikaev, E. V. Gavrilova, R. A. Maksyutov, G. V. Kochneva   +14 more
doaj   +1 more source

Ebola and Marburg virus vaccines [PDF]

Virus Genes, 2017
The filoviruses, Ebola virus (EBOV), and Marburg virus (MARV), are among the most pathogenic viruses known to man and the causative agents of viral hemorrhagic fever outbreaks in Africa with case fatality rates of up to 90%. Nearly 30,000 infections were observed in the latest EBOV epidemic in West Africa; previous outbreaks were much smaller ...
Reynolds, Pierce, Marzi, Andrea
openaire   +2 more sources

Marburg virus disease [PDF]

Postgraduate Medical Journal, 1973
Summary In the late summer of 1967 an epidemic in thirty-one patients in Germany and Yugoslavia of a disease transmitted from African green monkeys occurred; seven patients died. The incubation period was from 4 to 7 days. The main clinical features were headache, high fever, diarrhoea, a very characteristic rash, severe bleeding ...
openaire   +2 more sources

Shedding of Marburg Virus in Naturally Infected Egyptian Rousette Bats, South Africa, 2017

Emerging Infectious Diseases, 2020
We detected Marburg virus RNA in rectal swab samples from Egyptian rousette bats in South Africa in 2017. This finding signifies that fecal contamination of natural bat habitats is a potential source of infection for humans.
Janusz T. Pawęska, Nadia Storm, Wanda Markotter, Nicholas Di Paola, Michael R. Wiley, Gustavo Palacios, Petrus Jansen van Vuren   +6 more
doaj   +1 more source

Protective mAbs and Cross-Reactive mAbs Raised by Immunization with Engineered Marburg Virus GPs. [PDF]

PLoS Pathogens, 2015
The filoviruses, which include the marburg- and ebolaviruses, have caused multiple outbreaks among humans this decade. Antibodies against the filovirus surface glycoprotein (GP) have been shown to provide life-saving therapy in nonhuman primates, but ...
Marnie L Fusco, Takao Hashiguchi, Robyn Cassan, Julia E Biggins, Charles D Murin, Kelly L Warfield, Sheng Li, Frederick W Holtsberg, Sergey Shulenin, Hong Vu, Gene G Olinger, Do H Kim, Kevin J Whaley, Larry Zeitlin, Andrew B Ward, Cory Nykiforuk, M Javad Aman, Jody D Berry, Erica Ollmann Saphire   +18 more
doaj   +1 more source

Marburg Virus and Monkeypox Virus: The Concurrent Outbreaks in Ghana and the lesson learned from the Marburg Virus Containment

Journal of Pure and Applied Microbiology, 2022
Ghana, a country in the African continent experienced its first ever outbreak of Marburg Virus disease on July 2022. Prior to this, Democratic Republic of Congo and Angola were the two most severely affected countries to be affected by the same disease ...
Ranjit Sah, Abdullah Reda, Basant Ismail Lashin, Abdelaziz Abdelaal, Aroop Mohanty, Abdelmonem Siddiq, Bijaya Kumar Padhi   +6 more
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Marburgvirus in Egyptian Fruit Bats, Zambia

Emerging Infectious Diseases, 2019
We detected Marburg virus genome in Egyptian fruit bats (Rousettus aegyptiacus) captured in Zambia in September 2018. The virus was closely related phylogenetically to the viruses that previously caused Marburg outbreaks in the Democratic Republic of the
Masahiro Kajihara, Bernard M. Hang’ombe, Katendi Changula, Hayato Harima, Mao Isono, Kosuke Okuya, Reiko Yoshida, Akina Mori-Kajihara, Yoshiki Eto, Yasuko Orba, Hirohito Ogawa, Yongjin Qiu, Hirofumi Sawa, Edgar Simulundu, Daniel Mwizabi, Musso Munyeme, David Squarre, Victor Mukonka, Aaron Mweene, Ayato Takada   +19 more
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Knowledge and attitude towards Ebola and Marburg virus diseases in Uganda using quantitative and participatory epidemiology techniques.

PLoS Neglected Tropical Diseases, 2017
BackgroundUganda has reported five (5) Ebola virus disease outbreaks and three (3) Marburg virus disease outbreaks from 2000 to 2016. Peoples' knowledge and attitude towards Ebola and Marburg virus disease impact on control and prevention measures ...
Luke Nyakarahuka, Eystein Skjerve, Daisy Nabadda, Doreen Chilolo Sitali, Chisoni Mumba, Frank N Mwiine, Julius J Lutwama, Stephen Balinandi, Trevor Shoemaker, Clovice Kankya   +9 more
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