Results 81 to 90 of about 5,696,603 (212)

Selection of Filovirus Isolates for Vaccine Development Programs

Vaccines, 2021
The continuing outbreaks of ebola virus disease highlight the ongoing threat posed by filoviruses. Fortunately, licensed vaccines and therapeutics are now available for Zaire ebolavirus.
Daniel N. Wolfe, Carol L. Sabourin, Michael J. Merchlinsky, William C. Florence, Larry A. Wolfraim, Kimberly L. Taylor, Lucy A. Ward   +6 more
doaj   +1 more source

Causes and Outcome of Systemic Inflammatory Response Syndrome in Dogs: An Observational Study of 172 Cases

Journal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To evaluate the clinical characteristics, underlying diseases, organ dysfunctions, and survival of dogs with systemic inflammatory response syndrome (SIRS) or sepsis. Design Prospective observational study from January to December, 2023. Setting Single‐center, veterinary university teaching hospital.
Myriam A. Knopf, Christiane Weingart, Roswitha Merle, Teresa Sandbrink, Antina Lübke‐Becker, Marcus Fulde, Caroline Robé, Marianne Skrodzki, Uwe Rösler, Stefan Schwarz, Barbara Kohn   +10 more
wiley   +1 more source

Rwanda’s lessons for strengthening Africa’s response to current Marburg virus disease outbreaks

The Lancet Global Health
Summary: Marburg virus disease remains a major threat to global health security in Africa, where recurrent filovirus outbreaks intersect with fragile health systems.
Claude Mambo Muvunyi, Prof, Pierre Gashema, MSc, Eric Seruyange, PhD, ProfPhD Theogene Twagirumugabe, PhD, Isabelle Mukagatare, MD, Patrick Gad Iradukunda, MSc, Radjabu Bigirimana, MD, Emmanuel Edwar Siddig, PhD, Edson Rwagasore, MD, Jean de Dieu Harelimana, PhD, ProfPhD Sanctus Musafiri, PhD   +10 more
doaj   +1 more source

Development of an Immunochromatography Assay to Detect Marburg Virus and Ravn Virus

Viruses, 2023
The recent outbreaks of Marburg virus disease (MVD) in Guinea, Ghana, Equatorial Guinea, and Tanzania, none of which had reported previous outbreaks, imply increasing risks of spillover of the causative viruses, Marburg virus (MARV) and Ravn virus (RAVV),
Katendi Changula, Masahiro Kajihara, Shino Muramatsu, Koji Hiraoka, Toru Yamaguchi, Yoko Yago, Daisuke Kato, Hiroko Miyamoto, Akina Mori-Kajihara, Asako Shigeno, Reiko Yoshida, Corey W. Henderson, Andrea Marzi, Ayato Takada   +13 more
doaj   +1 more source

Variant‐Specific Landscape of Mutual Exclusivity Among BRAF, EGFR, and KRAS Oncogenes Reveals Overlap With Functionally Antagonistic Mutant Pairs

International Journal of Cancer, Volume 159, Issue 7, Page 1715-1734, 1 October 2026.
Mutual exclusivity and co‐occurrence of oncogenic mutations reflect functional antagonism or dependence and may inform therapeutic strategies. However, most studies overlook variant‐level patterns. In this comprehensive, cross‐cohort analysis of BRAF, KRAS, and EGFR mutation subtypes, the most significant mutual exclusivity pairs overlapped with ...
Freya Vaeyens, Jan‐Patrick Hetzel, Khaldoon Abdullah, Carolien Eggermont, Catharina Olsen, Marco Mernberger, Ken Maes, Jelle Vlaeminck, Rainer Claus, Dries Vanisterbecq, Frederik Hes, Martin Pichler, Philippe Giron, Oleg Timofeev, Maxim Noeparast   +14 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, Volume 600, Issue 17, Page 2526-2546, September 2026.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Mapping the zoonotic niche of Marburg virus disease in Africa [PDF]

Transactions of The Royal Society of Tropical Medicine and Hygiene, 2015
Marburg virus disease (MVD) describes a viral haemorrhagic fever responsible for a number of outbreaks across eastern and southern Africa. It is a zoonotic disease, with the Egyptian rousette (Rousettus aegyptiacus) identified as a reservoir host.
Pigott, DM, Golding, N, Mylne, A, Huang, Z, Weiss, DJ, Brady, OJ, Kraemer, MUG, Hay, SI   +7 more
openaire   +4 more sources

Mathematical Modeling of Pulse‐Seeded Metapopulation Dynamics for Andes Hantavirus Border Dispersal

Engineering Reports, Volume 8, Issue 9, September 2026.
A pulse‐seeded metapopulation SEIR model for Andes hantavirus maritime dispersal shows that heterogeneous quarantine compliance determines secondary outbreak risk. The weakest‐compliance country governs global containment, while uniform compliance above ∼65%$$ \sim 65\% $$ reduces the global reproduction number below unity.
Gideon K. Gogovi, Paul Chataa
wiley   +1 more source

Top 10 Public Health Challenges in 2025: Lessons and Priorities for 2025–2030

Public Health Challenges, Volume 5, Issue 3, September 2026.
ABSTRACT By 2025, global public health will be shaped by interconnected and intensifying threats that demand coordinated international action. Ten key public health challenges were identified and examined. This perspective reviews the challenges that shaped 2025 and the priorities set for the period 2025–2030, using evidence available up to July 2026 ...
Don Eliseo Lucero Prisno III, Mohamed Mustaf Ahmed, Zhinya Kawa Othman, Rahmatullah Nazari, Uthman Okikiola Adebayo, Olalekan John Okesanya, Shuaibu Saidu Musa, Francesco Branda, Abdullahi Hassan Elmi, Jerico Bautista Ogaya   +9 more
wiley   +1 more source

Marburg Virus Disease in Tanzania: A Review

Clinical Infection in Practice
Vaishnavi Akshay Patel, Amogh Verma, Manali Verma, Sourav Sudan, Amna Zaheer, Anil Kumar, Hajira Karim, Shubham Kumar, Rachana Mehta, Ranjana Sah   +9 more
doaj   +2 more sources