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Pathogenesis of Marek’s Disease Virus Infection
2001The term pathogenesis is most simply defined as the development of disease. Many uncomplicated infectious diseases proceed in a direct fashion from infection to a specific pathologic expression. However, other diseases are relatively complex in terms of pathogenesis; Marek’s disease (MD) most certainly belongs in this category.
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Effect of Phosphonoacetate on Marek's Disease Virus Replication
JNCI: Journal of the National Cancer Institute, 1976Phosphonoacetate (PA), but not any of its analogues tested, effectively inhibited avian herpesvirus replication and viral DNA synthesis in cell cultures. At 100 mug/ml culture medium, PA completely inhibited the replication of Marek's disease virus (MDV), herpesvirus of turkeys, and owl herpesvirus, but had no measurable effect on normal cell growth ...
L F, Lee +4 more
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Marek's disease virus: from miasma to model
Nature Reviews Microbiology, 2006Marek's disease virus (MDV) is an oncogenic herpesvirus that causes various clinical syndromes in its natural host, the chicken. MDV has long been of interest as a model organism, particularly with respect to the pathogenesis and immune control of virus-induced lymphoma in an easily accessible small-animal system.
Osterrieder, Nikolaus +4 more
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Disinfection of Marek's disease virus in poultry dust
Avian Pathology, 1977Dust samples from farms contaminated with Marek's disease virus (MDV) were exposed to various disinfectants under experimental and field conditions. After the disinfection treatment, examination was made for the presence and oncogenicity of surviving MDV by the inoculation of tissue cultures and susceptible chickens.
I, Hlozanek, V, Jurajda, V, Benda
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Immune Responses to Marek’s Disease Virus Infection
2001Marek’s disease (MD), a herpesvirus-induced lymphomatous disease in chickens, has attracted the interest of immunologists since MD virus (MDV) was isolated in 1968 and vaccines became available shortly afterwards (Witter 1985,Witter 2000). The pathogenesis of MD has been reviewed extensively (Calnek 1986,Calnek 1998,Calnek 2000; Schat 1987b). Infection
K A, Schat, C J, Markowski-Grimsrud
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T-cell transformation by Marek's disease virus
Trends in Microbiology, 1999Marek's disease virus (MDV) is an avian herpesvirus that causes rapid development of T-cell lymphomas in chickens. The MDV genes currently thought to be involved in lymphomagenesis include a bZIP transactivator that is homologous to fos and jun oncogenes but do not appear to have counterparts in other oncogenic herpesviruses.
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[Morphogenesis of Marek's disease virus in cell culture].
Virologie (Montrouge, France), 2007National ...
Denesvre, Caroline, Blondeau, Caroline
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