Results 11 to 20 of about 486,062 (218)

Viral miRNA delivered by exosomes from Marek's disease virus-transformed lymphoma cell line exerts regulatory function in internalized primary chicken embryo fibroblast cells [PDF]

Tumour Virus Research
In the past decade, research has demonstrated that viral miRNAs encoded by a number of viral genomes, particularly by most of the herpesvirus including Marek's disease virus (MDV), play important regulatory roles in viral infection, replication, and ...
Man Teng, Jun Luo, Yaoyao Zhang, Vishwanatha R.A.P. Reddy, Priya Samuel, Yongxiu Yao, Venugopal Nair   +6 more
doaj   +2 more sources

Immunopotentiating effect of lentinan on chicks and its inhibitory effect on Marek's disease virus infection [PDF]

Poultry Science
: Marek's disease virus (MDV) is a significant tumorigenic virus that causes severe immunosuppression in chickens. Lentinan (LNT) is an immunomodulator containing β-glucans and is widely used in areas such as antiviral, anticancer, and immune regulation.
Qiming Gao, Shun Li, Wanli Sun, Hongjian Yan, Yixin Wang, Shuang Chang, Peng Zhao   +6 more
doaj   +2 more sources

Comprehensive Analysis of Liver Transcriptome and Metabolome Response to Oncogenic Marek’s Disease Virus Infection in Wenchang Chickens [PDF]

Biology
Marek’s disease (MD), induced by the highly contagious Marek’s disease virus (MDV), remains a significant challenge to global poultry health despite extensive vaccination efforts.
Lifeng Zhi, Xiangdong Xu, Yang Zeng, Wenquan Qin, Ganghua Li, Junming Zhao, Runfeng Zhang, Guang Rong   +7 more
doaj   +2 more sources

Recombinant Marek’s disease virus expressing VP1 and VP2 proteins provides robust immune protection against chicken infectious anemia virus [PDF]

Frontiers in Microbiology
Chicken infectious anemia (CIA) is a highly contagious disease caused by the chicken infectious anemia virus (CIAV), and it poses a serious threat to the poultry industry. However, effective control measures and strategies have not been identified.
Chengfei Ge, Hangqiong Lu, Jinze Han, Guorong Sun, Shihao Li, Xingge Lan, Yongzhen Liu, Mengmeng Yu, Xinyun Hu, Mingxue Hu, Xiaole Qi, Hongyu Cui, Yulu Duan, Suyan Wang, Yuntong Chen, Xiaomei Wang, Xiaomei Wang, Yanping Zhang, Yulong Gao, Changjun Liu   +19 more
doaj   +2 more sources

Marek's disease virus-1 unique gene LORF1 is involved in viral replication and MDV-1/Md5-induced atrophy of the bursa of Fabricius. [PDF]

PLoS Pathogens
Marek's disease virus (MDV), an alphaherpesvirus, causes severe immunosuppression and T cell lymphomas in chickens, known as Marek's disease (MD), an economically important poultry disease primarily controlled by vaccination.
Chenyi Bao, Jun Chu, Qi Gao, Shasha Yang, Xiaoyu Gao, Wenwen Chen, Fuchun Yang, Fei Jiang, Chenxi Tong, Mingyi Lei, Linlin Jiao, Jitong Li, Kexin Wei, Xue Lian, Kai Li, Suresh Kumar Tikoo, Nikolaus Osterrieder, Lorne A Babiuk, Yufeng Li, Yong-Sam Jung, Yingjuan Qian   +20 more
doaj   +2 more sources

Emerging Hypervirulent Marek’s Disease Virus Variants Significantly Overcome Protection Conferred by Commercial Vaccines

Viruses, 2023
As one of the most important avian immunosuppressive and neoplastic diseases, Marek’s disease (MD), caused by oncogenic Marek’s disease virus (MDV), has caused huge economic losses worldwide over the past five decades.
Jin-ling Liu, M. Teng, Luping Zheng, F. Zhu, Shu-Xue Ma, Lin-Yan Li, Zhi-Hui Zhang, S. Chai, Yongxiu Yao, Jun Luo   +9 more
semanticscholar   +1 more source

Effect of Insertion and Deletion in the Meq Protein Encoded by Highly Oncogenic Marek’s Disease Virus on Transactivation Activity and Virulence

Viruses, 2022
Marek’s disease virus (MDV) causes malignant lymphoma in chickens (Marek’s disease, MD). Although MD is currently controlled by vaccination, MDV strains have continuously increased in virulence over the recent decades.
Jumpei Sato, S. Murata, Zhiyuan Yang, B. Kaufer, Sotaro Fujisawa, Hikari Seo, N. Maekawa, T. Okagawa, S. Konnai, N. Osterrieder, M. Parcells, K. Ohashi   +11 more
semanticscholar   +1 more source

The Regulatory Microenvironment in Feathers of Chickens Infected with Very Virulent Marek’s Disease Virus

Viruses, 2022
Vaccines against Marek’s disease can protect chickens against clinical disease; however, infected chickens continue to propagate the Marek’s disease virus (MDV) in feather follicles and can shed the virus into the environment.
Jegarubee Bavananthasivam, Nadiyah Alqazlan, Mohammadali Alizadeh, Ayumi Matsuyama-Kato, Jake Astill, Raveendra R. Kulkarni, Shayan Sharif   +6 more
doaj   +1 more source

Differential Virus-Specific IFN-Gamma Producing T Cell Responses to Marek’s Disease Virus in Chickens With B19 and B21 MHC Haplotypes

Frontiers in Immunology, 2022
Marek’s disease virus (MDV), the etiologic agent for Marek’s disease (MD), causes a deadly lymphoproliferative disease in chickens. Causes of the well-documented association between genetically defined lines of chicken and resistance to MD remain unknown.
Nitish Boodhoo, S. Behboudi
semanticscholar   +1 more source

Analysis of DNA methylation of CD79B in MDV-infected chicken spleen

Journal of Integrative Agriculture, 2021
Marek's disease (MD), an immunosuppressive disease induced by Marek's disease virus (MDV), provides an ideal model for studying diseases caused by a carcinogenic virus. CD79B is a B-cell antigen receptor complex-associated protein β-chain precursor which
Lu-lu WANG, Chun-fang ZHAO, Chang-jun LIU, Hao ZHANG, Ling LIAN   +4 more
doaj   +1 more source