Results 31 to 40 of about 5,626,005 (151)
An Overview on Marek’s Disease Virus Evolution and Evidence for Increased Virulence in Brazil
Marek’s disease virus (MDV) has been shown to be evolving to higher virulence. One of the genetic sites involved in virulence which enables such characterization is the 339-amino acid Meq protein encoding gene (meq).
ACD Torres +3 more
doaj +1 more source
Marek's disease herpesvirus serotype 1 in broiler breeder and layer chickens in Malaysia [PDF]
Aim: This study aimed to investigate the occurrence of Marek's disease (MD) in five poultry farms in Malaysia using postmortem examination, histopathology, and polymerase chain reaction (PCR).
Iryanti Othman, Erkihun Aklilu
doaj +1 more source
Protection against Marek's disease by a fowlpox virus recombinant expressing the glycoprotein B of Marek's disease virus [PDF]
Fowlpox virus (FPV) recombinants expressing the glycoprotein B and the phosphorylated protein (pp38) of the GA strain of Marek's disease virus (MDV) were assayed for their ability to protect chickens against challenge with virulent MDV. The recombinant FPV expressing the glycoprotein B gene elicited neutralizing antibodies against MDV, significantly ...
K, Nazerian +3 more
openaire +2 more sources
Serotype and strain specific molecular differentiation of Marek's disease virus
[Extract] Marek's disease (MD) is a lymphoproliferative disease of chickens caused by an avian herpesvirus, Marek's disease virus (MDV). There are three recognised serotypes (1, 2 and 3) of which only serotype 1 is pathogenic (Churchill & Biggs, 1967 ...
Layton, R.D., Burgess, G.W.
core +2 more sources
A genomic investigation of Marek's disease lymphomas [PDF]
"Meq, a bZIP transcription factor and the viral oncogene for pathogenic strains of Marek's disease virus (MDV), is required to induce CD4 T cell lymphomas that characterize Marek's disease (MD) in chickens.
Steep, Alexander Cordiner
core +1 more source
This datasheet on Marek's disease covers Identity, Overview, Associated Diseases, Pests or Pathogens, Distribution, Hosts/Species Affected, Diagnosis, Pathology, Epidemiology, Impacts, Prevention/Control, Further ...
Shahriar Behboudi, Behboudi, Shahriar
core +1 more source
The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang +10 more
wiley +1 more source
Early synovial regulatory T cell engagement in posttraumatic osteoarthritis
Objective Posttraumatic osteoarthritis (PTOA) develops despite restoration of joint biomechanics, suggesting that early post‐injury biological processes within the synovium shape disease trajectories. We investigated whether synovial regulatory T (Treg) cells are engaged during the early phase following joint injury and whether experimental enrichment ...
Xueyou Zhang +5 more
wiley +1 more source
Marek's disease, an economically important disease of chickens caused by virulent serotype 1 strains of the Mardivirus Marek's disease virus (MDV-1), is effectively controlled in the field by live attenuated vaccine viruses including herpesvirus of ...
Giulia Mescolini +3 more
doaj +1 more source
ABSTRACT Background Head and neck cancer (HNC) is a devastating diagnosis, with advanced‐stage disease leading to poorer outcomes. This qualitative study aimed to identify health system factors associated with stage of HNC diagnosis. Methods Qualitative semistructured interviews with HNC patients and clinicians were undertaken in two purposively ...
Grant Creaney +196 more
wiley +1 more source

