Results 51 to 60 of about 2,698 (157)

Transcription of the Marek's Disease Virus Genome in Virus-Induced Tumors [PDF]

open access: yesJournal of Virology, 1979
Transcription of the Marek's disease virus (MDV) genome in tumor tissues from MDV-infected chickens has been studied by analyzing the hybridization kinetics of 3 H-labeled MDV DNA with unlabeled RNA extracted from these tissues. Lymphoid tumors of ovary, spleen, liver, and kidney contained MDV genomes, but the virus-
S, Silver, M, Smith, M, Nonoyama
openaire   +2 more sources

Unraveling Oral Dysbiosis: Microbial Complexity in Common Oral Diseases

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
The oral microbiome undergoes dynamic establishment from birth, maturing into a resilient ecosystem. Perturbation of this homeostasis—driven by dietary, immunological, and anatomical factors—triggers dysbiosis, which underpins the pathogenesis of major oral diseases, including dental caries, periodontal disease, salivary gland disorders, oral mucosal ...
Zixi Kang   +8 more
wiley   +1 more source

Deoxyribonucleic Acid of Marek's Disease Virus in Virus-Induced Tumors [PDF]

open access: yesJournal of Virology, 1973
DNA was extracted from [ 3 H]thymidine-labeled Marek's disease virus (MDV) and purified by two cycles of CsCl gradient centrifugation in a fixed-angle rotor. The DNA was transcribed in vitro into 32 P-labeled complementary RNA (cRNA).
K, Nazerian   +3 more
openaire   +2 more sources

Farmed Escapees Threaten MHC Diversity in Wild Atlantic Salmon

open access: yesEvolutionary Applications, Volume 19, Issue 6, June 2026.
ABSTRACT Wild Atlantic salmon populations in Norway and elsewhere are experiencing long‐term declines driven by reduced marine survival, climate change, impacts from aquaculture, introduction of alien species, and environmental degradation. Understanding how immune diversity is affected by these declines, and thus the ability of Atlantic salmon to ...
Morten Lukacs   +9 more
wiley   +1 more source

PERCC1‐associated enteropathy: Diagnostic challenges and enteral autonomy achieved with teduglutide

open access: yesJPGN Reports, Volume 7, Issue 2, Page 266-270, May 2026.
Abstract Congenital diarrheas and enteropathies (CODE) are rare inherited disorders characterized by early‐onset intractable diarrhea. Though progress has been made in elucidating the genetic basis of CODE, much remains to be discovered. Another challenge is the lack of curative therapies—treatment is primarily supportive including enteral and ...
Angela Tran, Vivien Nguyen, Phuong Huynh
wiley   +1 more source

Genome‐Wide Assessment Reveals Ancestral Differences in Homozygosity Patterns Potentially Linked to Parkinson's Disease Etiology

open access: yesMovement Disorders, Volume 41, Issue 5, Page 1128-1140, May 2026.
Abstract Background Recessive genetic variation and extended runs of homozygosity (ROHs) may contribute to the unexplained heritability of Parkinson's disease (PD), particularly in diverse and understudied populations. Objective We conducted the first large‐scale, multi‐ancestral investigation of PD to examine the impact of genome‐wide homozygosity on ...
Kathryn Step   +680 more
wiley   +1 more source

Immunosuppressive effect of Marek's disease virus in broiler [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2005
تمت دراسة التأثیر المناعی المثبط للاصابة التجریبیة بفایروس مرض میرک فی فروج اللحم على مستوى المناعة المتکونة عند تلقیح حیوانات التجربة بلقاح مرض نیوکاسل وقد تم الکشف عن مستوى الأضداد المناعیة باستخدام اختبار تثبیط التلازن الدموی، حیث أظهرت نتائج هذا ...
Mozahim Al-Attar
doaj   +1 more source

DNA Configuration in the Core of Marek's Disease Virus [PDF]

open access: yesJournal of Virology, 1974
Marek's disease virus DNA appears to be wound around a central structure connecting the two inner poles of the capsid. Based on electron micrographs of Marek's disease virions, a diagram of spatial configuration of virus DNA is presented. This diagram may explain the pleomorphic character of the herpesvirus core observed with the electron microscope.
openaire   +2 more sources

Discordance of Dopaminergic Dysfunction and Subcortical Atrophy by α‐Synuclein Status in Sporadic and Genetic Parkinson's Disease

open access: yesMovement Disorders, Volume 41, Issue 5, Page 1101-1113, May 2026.
Abstract Background Parkinson's disease (PD) is characterized by predominantly neuronal α‐synuclein pathology and dopaminergic dysfunction. Cerebrospinal fluid (CSF) seeding amplification assays (SAA) detect α‐synuclein aggregates in vivo, but not all patients with PD have a positive SAA.
Michael Tran Duong   +186 more
wiley   +1 more source

Structural and functional insights into TBC1D17 highlight the importance of the previously uncharacterized Rab‐binding domain

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract TBC (Tre2/Bub2/Cdc16) domain‐containing proteins constitute the widespread family of GTPase‐activating proteins (GAPs). They interact with the Rab superfamily of small GTPases, stimulate GTP hydrolysis, and regulate vesicle trafficking. TBC1D17, involved in Shiga toxin trafficking, autophagy and glucose metabolism regulation, constitutes an ...
Dominika Nielipińska   +6 more
wiley   +1 more source
3. good health
animals
marek disease
chickens
herpesvirus 2, gallid
marek’s disease virus
poultry diseases
dna, viral
herpesviridae
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