Results 71 to 80 of about 5,626,005 (151)

PERCC1‐associated enteropathy: Diagnostic challenges and enteral autonomy achieved with teduglutide

open access: yesJPGN Reports, Volume 7, Issue 2, Page 266-270, May 2026.
Abstract Congenital diarrheas and enteropathies (CODE) are rare inherited disorders characterized by early‐onset intractable diarrhea. Though progress has been made in elucidating the genetic basis of CODE, much remains to be discovered. Another challenge is the lack of curative therapies—treatment is primarily supportive including enteral and ...
Angela Tran, Vivien Nguyen, Phuong Huynh
wiley   +1 more source

A novel immune evasion gene of Marek's Disease Virus [PDF]

open access: yes, 2012
Marek's Disease Virus, a lymphotrophic, oncogenic alpha-herpesvirus of chickens, has historically presented a significant vaccine challenge to the poultry industry, and is also a useful model for herpesviral vaccine development. Herpesviruses impact both
Hearn, Cari Jacqueline
core   +1 more source

Marek’s Disease Virus (Gallid alphaherpesvirus 2)-Encoded miR-M2-5p Simultaneously Promotes Cell Proliferation and Suppresses Apoptosis Through RBM24 and MYOD1-Mediated Signaling Pathways

open access: yesFrontiers in Microbiology, 2020
MicroRNAs (miRNAs) have been demonstrated for their involvement in virus biology and pathogenesis, including functioning as key determinants of virally-induced cancers.
Zhi-Jian Zhu   +20 more
doaj   +1 more source

Genome‐Wide Assessment Reveals Ancestral Differences in Homozygosity Patterns Potentially Linked to Parkinson's Disease Etiology

open access: yesMovement Disorders, Volume 41, Issue 5, Page 1128-1140, May 2026.
Abstract Background Recessive genetic variation and extended runs of homozygosity (ROHs) may contribute to the unexplained heritability of Parkinson's disease (PD), particularly in diverse and understudied populations. Objective We conducted the first large‐scale, multi‐ancestral investigation of PD to examine the impact of genome‐wide homozygosity on ...
Kathryn Step   +680 more
wiley   +1 more source

Multiplication of Turkey herpes virus and Marek's disease virus in chick embryo skin cell cultures

open access: yes, 1977
A simple method for the in vitro cultivation of chick embryo skin epithelial cells was developed and the replication of turkey herpes virus (HVT) and Marek's disease herpes virus (MDHV) in this system was studied. A high percentage of cells in monolayers
Spradbrow P.B., Prasad L.B.M.
core   +1 more source

Use of Recombinant Virus Replicon Particles for Vaccination against Mycobacterium ulcerans Disease. [PDF]

open access: yes, 2015
Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a necrotizing disease of the skin and subcutaneous tissue, which is most prevalent in rural regions of West African countries.
Kerber, Sarah   +11 more
core   +3 more sources

Viral miRNA delivered by exosomes from Marek's disease virus-transformed lymphoma cell line exerts regulatory function in internalized primary chicken embryo fibroblast cells

open access: yesTumour Virus Research
In the past decade, research has demonstrated that viral miRNAs encoded by a number of viral genomes, particularly by most of the herpesvirus including Marek's disease virus (MDV), play important regulatory roles in viral infection, replication, and ...
Man Teng   +6 more
doaj   +1 more source

Discordance of Dopaminergic Dysfunction and Subcortical Atrophy by α‐Synuclein Status in Sporadic and Genetic Parkinson's Disease

open access: yesMovement Disorders, Volume 41, Issue 5, Page 1101-1113, May 2026.
Abstract Background Parkinson's disease (PD) is characterized by predominantly neuronal α‐synuclein pathology and dopaminergic dysfunction. Cerebrospinal fluid (CSF) seeding amplification assays (SAA) detect α‐synuclein aggregates in vivo, but not all patients with PD have a positive SAA.
Michael Tran Duong   +186 more
wiley   +1 more source

Diagnostic investigation of Marek's disease in a turkey [PDF]

open access: yes, 2016
A six‐month‐old female turkey from a commercial growing unit was evaluated at postmortem examination for investigation of suspected viral lymphoproliferative disease.
Joy Archer   +4 more
core   +2 more sources

Effect of Biodiversity Changes in Disease Risk: Exploring Disease Emergence in a Plant-Virus System [PDF]

open access: yes, 2012
The effect of biodiversity on the ability of parasites to infect their host and cause disease (i.e. disease risk) is a major question in pathology, which is central to understand the emergence of infectious diseases, and to develop strategies for their ...
Daniel Piñero (154115)   +33 more
core   +1 more source

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