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Marek’s Disease Virus Infection of Natural Killer Cells
Natural killer (NK) cells are key players in the innate immune response. They kill virus-infected cells and are crucial for the induction of adaptive immune responses. Marek's disease virus (MDV) is a highly contagious alphaherpesvirus that causes deadly
Luca D. Bertzbach +4 more
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The Genome of a Very Virulent Marek's Disease Virus
ABSTRACT Here we present the first complete genomic sequence, with analysis, of a very virulent strain of Marek's disease virus serotype 1 (MDV1), Md5. The genome is 177,874 bp and is predicted to encode 103 proteins. MDV1 is colinear with the prototypic alphaherpesvirus herpes simplex virus type 1 (HSV-1) within the unique long (UL) region ...
E R, Tulman +5 more
openaire +3 more sources
Expression of matrix metalloproteinases in Marek's disease tumours
Marek's disease is an important lymphoproliferative neoplasm of chickens, caused by oncogenic strains of herpes virus. Visceral lymphomas and invasion of both central nervous tissues and peripheral nerves by lymphoid cells are common findings.
core +1 more source
'In vitro' and 'in vivo' characterization of selected Australian isolates of Marek's disease virus [PDF]
Chapter 1 reviews the literature on Marek's disease relevant to the work carried out in this thesis. Methods for TaqMan® quantitative real-time PCR (qPCR) assays to detect the three serotypes of Marek's disease virus (MDV) are already available, and ...
Islam, A Fakhrul +3 more
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Abstracts of 14th International Symposium on Hodgkin Lymphoma
HemaSphere, Volume 10, Issue S2, October 2026.
wiley +1 more source
Unraveling the role of γδ T cells in the pathogenesis of an oncogenic avian herpesvirus
Marek’s disease virus (MDV) is an oncogenic alphaherpesvirus that causes deadly lymphomas in chickens. In chickens, up to 50% of all peripheral T cells are gamma delta (γδ) T cells.
Mohammad A. Sabsabi +8 more
doaj +1 more source
Molecular and immunogenic analysis of Jembrana disease virus Tat [PDF]
Jembrana disease is an acute and severe disease of Bali cattle (Bos javanicus) endemic in Indonesia that is caused by a bovine lentivirus designated Jembrana disease virus (JDV).
Setiyaningsih, Surachmi
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Chicken infectious anemia (CIA) is a highly contagious disease caused by the chicken infectious anemia virus (CIAV), and it poses a serious threat to the poultry industry. However, effective control measures and strategies have not been identified.
Chengfei Ge +19 more
doaj +1 more source
Vaccination is the most effective preventative measure against economically devastating poultry diseases, such as infectious bursal disease (IBD), H9 subtype avian influenza (AI), and Marek’s disease.
Wenrui Fan +16 more
doaj +1 more source
Marek’s disease (MD), caused by pathogenic Marek’s disease virus serotype 1 (MDV-1), is one of the most important avian immunosuppressive and neoplastic diseases and has led to huge economic losses to the poultry industry worldwide.
Wen-Kai Zhang +9 more
doaj +1 more source

