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This archival publication may not reflect current scientific knowledge or recommendations. Current information available from the University of Minnesota Extension: https://www.extension.umn.edu.Halvorson, David A.. (1980).
Halvorson, David A.
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Genetic Resistance to Marek's Disease Virus and a Transplantable Marek's Disease Lymphoma.
Kawasaki, Yuuji +2 more
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Genomics and Marek’s disease virus
Cytogenetic and Genome Research, 2007Marek’s disease virus (MDV), a lymphotrophic alphaherpesvirus of chickens, causes a disease that is characterized by tumor formation, immunosuppression and neurological disorders. Recent developments in chicken genomics have been applied to studies of MDV and have advanced our understanding of both the virus and the disease it causes.
J, Burnside, R W, Morgan
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1985
Publisher Summary Marek's disease (MD)—a malignant lymphomatosis in chickens—is caused by Marek's disease virus (MDV) of the family Herpesviridae. This chapter reviews recent advances in MD research, especially in the field of molecular biology. Various antigens present in MDV virions, MDV-infected cells, or MD lymphoma cells have been suspected as ...
S, Kato, K, Hirai
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Publisher Summary Marek's disease (MD)—a malignant lymphomatosis in chickens—is caused by Marek's disease virus (MDV) of the family Herpesviridae. This chapter reviews recent advances in MD research, especially in the field of molecular biology. Various antigens present in MDV virions, MDV-infected cells, or MD lymphoma cells have been suspected as ...
S, Kato, K, Hirai
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Marek's Disease Virus Morphogenesis
Avian Diseases, 2013Marek's disease virus (MDV) is a highly contagious virus that induces T-lymphoma in chicken. This viral infection still circulates in poultry flocks despite the use of vaccines. With the emergence of new virulent strains in the field over time, MDV remains a serious threat to the poultry industry.
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A study of vaccination against Marek's disease with an attenuated Marek's disease virus
Avian Pathology, 1974Approximately 2,000 day-old white leghorn chickens were distributed into 10 pens and half the pens vaccinated with the attenuated strain of HPRS-16. At 72 weeks of age, mortality from non-specific death and Marek's disease was 17.6% and 15.6% respectively, in vaccinated chickens compared with 14.2% and 51.7% in unvaccinated chickens.
C A, Jackson +4 more
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2001
MDV latency is defined as the persistence of the viral genome in the absence of production of infectious virus except during reactivation. A number of systems for studying MDV latency exist, and most involve the use of lymphoblastoid cells or tumors. It has been difficult to divorce latency and transformation.
R W, Morgan +6 more
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MDV latency is defined as the persistence of the viral genome in the absence of production of infectious virus except during reactivation. A number of systems for studying MDV latency exist, and most involve the use of lymphoblastoid cells or tumors. It has been difficult to divorce latency and transformation.
R W, Morgan +6 more
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Structural proteins of Marek's disease virus
Virology, 1972Abstract Marek's disease virus (MDV) was propagated in roller-bottle cultures of duck embryo fibroblasts and partially purified by sucrose gradient centrifugation. Analysis of viral protein by polyacrylamide gel electrophoresis revealed that at least eight proteins (designated VPI-VPVIII) were present in MDV. The VPI is the major viral protein.
J H, Chen +3 more
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The Genomic Structure of Marek’s Disease Virus
2001All herpesviruses contain linear, double-stranded DNA genome surrounded by a 100-nm diameter icosahedral protein capsid core consisting of 162 capsomers. In thin-section electron micrographs, an electron transparent region, termed the tegument, surrounds the capsid, which in turn is surrounded by a lipid-containing envelope.
R F, Silva, L F, Lee, G F, Kutish
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