Onset and long-term duration of immunity provided by a single vaccination with recombinant a Marek's disease virus with REV-LTR insertion. [PDF]
Dai J +8 more
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Construction of Recombinant Marek's Disease Virus Co-Expressing VP1 and VP2 of Chicken Infectious Anemia Virus. [PDF]
Li K +12 more
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Marek's disease virus protein kinase US3 inhibits DNA-sensing antiviral innate immunity via abrogating activation of NF-κB. [PDF]
Li K +12 more
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Marek's disease virus-encoded microRNA-M6-5p facilitates viral latent infection by targeting histone demethylase KDM2B. [PDF]
Zhou L +6 more
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Marek's disease virus-1 unique gene LORF1 is involved in viral replication and MDV-1/Md5-induced atrophy of the bursa of Fabricius. [PDF]
Bao C +20 more
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Genomics and Marek’s disease virus
Cytogenetic and Genome Research, 2007Marek’s disease virus (MDV), a lymphotrophic alphaherpesvirus of chickens, causes a disease that is characterized by tumor formation, immunosuppression and neurological disorders. Recent developments in chicken genomics have been applied to studies of MDV and have advanced our understanding of both the virus and the disease it causes.
J, Burnside, R W, Morgan
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Marek's Disease Virus Morphogenesis
Avian Diseases, 2013Marek's disease virus (MDV) is a highly contagious virus that induces T-lymphoma in chicken. This viral infection still circulates in poultry flocks despite the use of vaccines. With the emergence of new virulent strains in the field over time, MDV remains a serious threat to the poultry industry.
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Publisher Summary Marek's disease (MD)—a malignant lymphomatosis in chickens—is caused by Marek's disease virus (MDV) of the family Herpesviridae. This chapter reviews recent advances in MD research, especially in the field of molecular biology. Various antigens present in MDV virions, MDV-infected cells, or MD lymphoma cells have been suspected as ...
S, Kato, K, Hirai
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A study of vaccination against Marek's disease with an attenuated Marek's disease virus
Avian Pathology, 1974Approximately 2,000 day-old white leghorn chickens were distributed into 10 pens and half the pens vaccinated with the attenuated strain of HPRS-16. At 72 weeks of age, mortality from non-specific death and Marek's disease was 17.6% and 15.6% respectively, in vaccinated chickens compared with 14.2% and 51.7% in unvaccinated chickens.
C A, Jackson +4 more
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