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Pathogenesis of Marek’s Disease Virus Infection
2001The term pathogenesis is most simply defined as the development of disease. Many uncomplicated infectious diseases proceed in a direct fashion from infection to a specific pathologic expression. However, other diseases are relatively complex in terms of pathogenesis; Marek’s disease (MD) most certainly belongs in this category.
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Immune Responses to Marek’s Disease Virus Infection
2001Marek’s disease (MD), a herpesvirus-induced lymphomatous disease in chickens, has attracted the interest of immunologists since MD virus (MDV) was isolated in 1968 and vaccines became available shortly afterwards (Witter 1985,Witter 2000). The pathogenesis of MD has been reviewed extensively (Calnek 1986,Calnek 1998,Calnek 2000; Schat 1987b). Infection
K A, Schat, C J, Markowski-Grimsrud
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Disinfection of Marek's disease virus in poultry dust
Avian Pathology, 1977Dust samples from farms contaminated with Marek's disease virus (MDV) were exposed to various disinfectants under experimental and field conditions. After the disinfection treatment, examination was made for the presence and oncogenicity of surviving MDV by the inoculation of tissue cultures and susceptible chickens.
I, Hlozanek, V, Jurajda, V, Benda
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Avian Diseases, 2013
The role of pp38 in the pathogenesis of Marek's disease (MD) has not been fully elucidated. Previously, we reported the presence of two splice variants (Spl A and Spl B) for pp38. We also reported that the wild-type pp38 (WT), as well as the mutated pp38 (MUT), altered the oxidative phosphorylation pathway in infected cells.
Karel A, Schat +4 more
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The role of pp38 in the pathogenesis of Marek's disease (MD) has not been fully elucidated. Previously, we reported the presence of two splice variants (Spl A and Spl B) for pp38. We also reported that the wild-type pp38 (WT), as well as the mutated pp38 (MUT), altered the oxidative phosphorylation pathway in infected cells.
Karel A, Schat +4 more
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International Journal of Cancer, 1975
AbstractImmunity against Marek's disease was conferred by the use of non‐infectious materials extracted with non‐ionic detergents from cells infected with the attenuated strain of Marek's disease virus (MDV). Antibody‐free Rhode Island Red chicks were inoculated at 1 week of age with cell extracts emulsified in Freund's complete adjuvant and were given
F, Lesnik, L J, Ross
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AbstractImmunity against Marek's disease was conferred by the use of non‐infectious materials extracted with non‐ionic detergents from cells infected with the attenuated strain of Marek's disease virus (MDV). Antibody‐free Rhode Island Red chicks were inoculated at 1 week of age with cell extracts emulsified in Freund's complete adjuvant and were given
F, Lesnik, L J, Ross
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The Threat of Marek's Disease Virus Is Expanding
Microbe Magazine, 2007Despite the attention being paid to avian influenza and its potential to cause a pandemic among humans, the threat of avian diseases extends well beyond the influenza virus. Of particular interest to poultry producers are foodborne infectious bacteria such as Salmonella and Campylobacter spp., as well as several viruses, including those responsible for
MacLea, Kyle S., H., Hans, Cheng
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T-cell transformation by Marek's disease virus
Trends in Microbiology, 1999Marek's disease virus (MDV) is an avian herpesvirus that causes rapid development of T-cell lymphomas in chickens. The MDV genes currently thought to be involved in lymphomagenesis include a bZIP transactivator that is homologous to fos and jun oncogenes but do not appear to have counterparts in other oncogenic herpesviruses.
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[Morphogenesis of Marek's disease virus in cell culture].
Virologie (Montrouge, France), 2007National ...
Denesvre, Caroline, Blondeau, Caroline
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