Marek’s disease virus and skin interactions [PDF]
Marek's disease virus (MDV) is a highly contagious herpesvirus which induces immunosuppression and T-cell lymphoma in chicken. This virus still circulates in flocks despite forty years of vaccination, with important economical losses at the world level.
Couteaudier, Mathilde +1 more
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Deletion of the meq gene significantly decreases immunosuppression in chickens caused by pathogenic marek's disease virus [PDF]
Background Marek's disease virus (MDV) causes an acute lymphoproliferative disease in chickens, resulting in immunosuppression, which is considered to be an integral aspect of the pathogenesis of Marek's disease (MD).
Cui Zhizhong +5 more
doaj +2 more sources
Marek's disease virus (MDV) is a pathogen of chickens whose control has twice been undermined by pathogen evolution. Disease ecology is believed to be the main driver of this evolution, yet mathematical models of MDV disease ecology have never been ...
David A. Kennedy +2 more
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A novel protein-coding ORF72.2 gene was identified from Marek's disease virus strain CVI988 [PDF]
Marek's disease is a highly contagious disease of poultry characterized by rapid-on set of T-cell lymphomas, which is caused by Marek's disease virus (MDV), but its pathogenic mechanism is still not very clear.
Liu Ping +8 more
doaj +2 more sources
The Functionality of Marek's Disease Virus Us3 Protein [PDF]
Marek's disease (MD) is a lymphoproliferative disease of chickens caused by cell-associated Marek's disease virus (MDV). The Us3 protein kinase expressed by MDV has been shown to be involved in various stages of the viral life cycle.
McKinney, Caleb
core +6 more sources
Use o fDulbecco's modified eagle's medium DMEM/F12 HAM for Marek's disease virus cultivation in chicken embryo fibroblasts [PDF]
The opportunity of using Dulbecco's Modified Eagle's Medium DMEM/F12 Ham for Marek's disease cultivation in chicken embryo fibroblasts was studied. It was determined that if appropriate virus cultivation parameters are chosen the abovementioned medium ...
Ye. Yu. Khanyukova +2 more
doaj +1 more source
Marek’s disease (MD) is caused by an oncogenic alphaherpesvirus, a common lymphoproliferative inducing agent usually characterized by mononuclear cellular infiltrates, mostly T-cell lymphomas in various visceral organs and peripheral nerves. The genome is linear and made up of double-stranded DNA molecules of nearly 160–180 kb in size.
Blanca M. Lupiani +4 more
openaire +2 more sources
MAREK'S DISEASE HERPES VIRUS: A CYTOMEGALOVIRUS? [PDF]
The DNA of herpes viruses associated with Marek's disease of fowl contains 56-57 moles of guanine and cytosine per 100. The composition of its DNA and lack of infectiousness of cell-free preparations suggest that the herpes virus associated with Marek's disease belongs to the herpes virus group B which contains predominantly cytomegaloviruses.
L F, Lee +5 more
openaire +2 more sources
Differential cytokine responses following Marek's disease virus infection in chicken genotypes differing in resistance to Marek's disease [PDF]
The production of cytokine mRNAs, in addition to viral DNA, was quantified by real-time quantitative reverse transcription-PCR (RT-PCR) (cytokines) or PCR (virus) in splenocytes during the course of Marek's disease virus (MDV) infection in four inbred ...
Davison, T F, Kaiser, Pete, Underwood, G
core +1 more source
MiRNA expression signatures induced by Marek's disease virus infection in chickens [PDF]
MicroRNAs (miRNAs) are small, non-coding RNAs that regulate gene expression at the post-transcriptional level. Emerging evidence suggests that differential miRNA expression is associated with viral infection and cancer.
Shuang Chang +9 more
core +1 more source

