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Effect of Insertion and Deletion in the Meq Protein Encoded by Highly Oncogenic Marek’s Disease Virus on Transactivation Activity and Virulence [PDF]

open access: goldViruses, 2022
Marek’s disease virus (MDV) causes malignant lymphoma in chickens (Marek’s disease, MD). Although MD is currently controlled by vaccination, MDV strains have continuously increased in virulence over the recent decades.
Jumpei Sato   +11 more
doaj   +2 more sources

Two distinct polymorphisms in the basic region of Meq protein of marek’s disease virus alter pathological progression and clinical manifestations [PDF]

open access: goldVirology Journal
Background Marek’s disease virus (MDV) causes Marek’s disease (MD) in chickens, which is characterized by malignant lymphomas and neurological disorders.
Jumpei Sato   +14 more
doaj   +2 more sources

Marek’s disease in the holland white crested chickens [PDF]

open access: diamondVeterinarski Glasnik, 2016
Marek’s disease is a viral lymphoproliferative disease of poultry characterized by the creation of lymphoma in muscle, skin, eye or internal organs.
Spalević Ljiljana   +5 more
doaj   +2 more sources

Surveillance and Molecular Characterization of Marek’s Disease Virus (MDV) Strains Circulating in Tanzania

open access: greenViruses
Marek’s disease (MD) is a highly contagious and oncogenic viral disease of poultry, causing significant economic losses due to mortality and reduced performance. The rapid evolution of Marek’s disease virus (MDV) has been reported in poultry farms, often
Augustino Alfred Chengula   +2 more
doaj   +3 more sources

Outbreak of Marek’s Disease in Chicken Flocks with Uncommon Pattern of Gross Lesions [PDF]

open access: yesJournal of Veterinary and Animal Sciences, 2023
Marek’s disease is one of the highly contagious and oncogenic diseases of poultry that remains as a threat to the fast-growing poultry sector, even after proper vaccination.
R. Geethanjali   +4 more
doaj   +1 more source

A Review on the Marek’s Disease Outbreak and Its Virulence-Related meq Genovariation in Asia between 2011 and 2021

open access: yesAnimals, 2022
Marek’s disease is an infectious disease in poultry that usually appears in neural and visceral tumors. This disease is caused by Gallid alphaherpesvirus 2 infection in lymphocytes, and its meq gene is commonly used in virulent studies for coding the key
Baolin Song   +9 more
doaj   +1 more source

The Regulatory Microenvironment in Feathers of Chickens Infected with Very Virulent Marek’s Disease Virus

open access: yesViruses, 2022
Vaccines against Marek’s disease can protect chickens against clinical disease; however, infected chickens continue to propagate the Marek’s disease virus (MDV) in feather follicles and can shed the virus into the environment.
Jegarubee Bavananthasivam   +6 more
doaj   +1 more source

B cells do not play a role in vaccine-mediated immunity against Marek’s disease

open access: yesVaccine: X, 2022
Background: Marek’s disease virus (MDV), a highly oncogenic α-herpesvirus, is the etiological agent of Marek’s disease (MD) in chickens. The antiviral activity of vaccine-induced immunity against MD reduces the level of early cytolytic infection ...
Mohammad Heidari   +3 more
doaj   +1 more source

Occurrence of Marek’s disease in Poland on the basis of diagnostic examination in 2015–2018

open access: yesJournal of Veterinary Research, 2020
Marek’s disease (MD) is a tumourous disease caused by Marek’s disease virus (MDV) and most commonly described in poultry. The aim of the study was to determine the occurrence of Marek’s disease virus infections in Poland and analyse clinical cases in the
Kozdruń Wojciech   +5 more
doaj   +1 more source

The dominantly expressed class II molecule from a resistant MHC haplotype presents only a few Marek's disease virus peptides by using an unprecedented binding motif.

open access: yesPLoS Biology, 2021
Viral diseases pose major threats to humans and other animals, including the billions of chickens that are an important food source as well as a public health concern due to zoonotic pathogens.
Samer Halabi   +9 more
doaj   +1 more source

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