Results 91 to 100 of about 1,982,933 (271)

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

open access: yesAdvanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang   +10 more
wiley   +1 more source

Sea Ice Latent Heat Becomes More Active in the Arctic Sea Ice Energy Budget

open access: yesGeophysical Research Letters
Arctic sea ice has experienced rapid decrease in recent decades. The sea ice property changes have altered its thermodynamic processes, enhancing the heat exchange among atmosphere‐ocean‐ice surface.
Yuang Liu   +3 more
doaj   +1 more source

Integrated O2 and H2 Gas Therapy via Microneedle‐Assisted Photocatalytic Water Splitting for Accelerating Diabetic Full‐Thickness Skin Wound Healing

open access: yesAdvanced Science, EarlyView.
A concept of integrated O2 and H2 gas therapy is achieved using a gas‐producing material. PMP nanoparticles, fabricated from platinum, MIL‐101(Fe)‐NH2, and phosphotungstic acid, are integrated into bilayer gelatin methacryloyl microneedles for transdermal delivery. These microneedles enable integrated O2 and H2 gas therapy and promote wound healing via
Zesheng Chen   +13 more
wiley   +1 more source

Macrophage RSAD2 Couples mtDNA Synthesis With a Self‐Amplifying Inflammatory Circuit to Orchestrate Tissue Repair

open access: yesAdvanced Science, EarlyView.
Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan   +16 more
wiley   +1 more source

Spatiotemporal Variation Analysis of Ice-Edge Eddies in the Fram Strait Based on Sequential SAR Images

open access: yesJournal of Remote Sensing
The spatiotemporal dynamics of eddy formation, movement, and decay in marginal ice zones are pivotal to understanding oceanographic processes. While existing studies largely focus on identifying eddy locations and quantifying their distribution using ...
Xue Yang   +3 more
doaj   +1 more source

Call for marginal ice zone papers

open access: yesEos, Transactions American Geophysical Union, 1985
A special collection of papers that deal with physical processes in the marginal ice zones (MIZ's) is planned for publication in the Journal of Geophysical Research‐Oceans. It is anticipated that this collection will be primarily a forum for presentation of results from the East Greenland Sea Marginal Ice Zone Experiment (MIZEX East); however, results ...
openaire   +1 more source

Waves and Fetch in the Marginal Ice Zone [PDF]

open access: yes, 2012
Abstract : The long-term goal is to improve prediction of the arctic Marginal Ice Zone (MIZ) by improving basic understanding of the interaction between waves, sea ice, and open water (i.e., fetch). The primary objective is to improve wave source/sink parameterizations by directly measuring the growth and dissipation of waves in the MIZ.
openaire   +1 more source

Strong Metal‐Support Interaction Driven Janus Reconstruction in PtRu Alloys for Low‐Temperature Hydrogen Storage

open access: yesAdvanced Science, EarlyView.
Strong metal‐support interactions (SMSI) drive the spontaneous segregation of RuPt alloy into Janus nanoparticles on CeO2, spatially partitioning Pt‐rich domains for H2 dissociation and Ru‐rich domains for toluene adsorption. This Janus nanocatalysts yield a turnover frequency of 10 906 h−1 for toluene hydrogenation at 50 °C, which is 6.7 times that of
Xingyu Zhang   +5 more
wiley   +1 more source

Performance Analysis of an Ice-Based Buoy Operating from the Packed Ice Zone to the Marginal Ice Zone with an Imaging System

open access: yesJournal of Marine Science and Engineering
Arctic sea ice can be regarded as a sensitive indicator of climate change, and it has declined dramatically in recent decades. The swift decline in Arctic sea ice coverage leads to an expansion of the marginal ice zone (MIZ).
Guangyu Zuo, Haocai Huang, Huifang Chen
doaj   +1 more source

Near‐Infrared Fluorescent PROTAC Enables Theranostic Imaging and Selective Tau Degradation in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Here, we report a novel NIR fluorescent PROTAC platform that enables real‐time imaging and targeted degradation of Alzheimer's p‐Tau. Our lead compound effectively clears p‐Tau, reduces APP/Aβ, and alleviates cognitive deficits in AD mice. This work demonstrates a theranostic strategy for visualizing degradation and developing next‐generation AD ...
Ziwei Ren   +11 more
wiley   +1 more source

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