Results 81 to 90 of about 2,156 (171)

EMMPRIN/CD147 up-regulates urokinase-type plasminogen activator: implications in oral tumor progression

BMC Cancer, 2012
Backgrounds An elevated level of EMMPRIN in cancer tissues have been correlated with tumor invasion in numerous cancers including oral cavity and larynx.
Lescaille Géraldine, Menashi Suzanne, Cavelier-Balloy Bénédicte, Khayati Farah, Quemener Cathy, Podgorniak Marie, Naïmi Benyoussef, Calvo Fabien, Lebbe Céleste, Mourah Samia   +9 more
doaj   +1 more source

Identification of AS1842856 as a novel small‐molecule GSK3α/β inhibitor against Tauopathy by accelerating GSK3α/β exocytosis

Aging Cell, Volume 24, Issue 1, January 2025.
AS1842856 (AS) inhibits Tauopathy via promoting glycogen synthase kinase‐3α/β (GSK3α/β) exocytosis. Upon entering the cell, AS binds to GSK3α/β and facilitates the translocation of GSK3α/β to early endosomes, which in turn promotes GSK3α/β accumulation in multivesicular bodies (MVBs) and subsequently reduces intracellular GSK3α/β contents via promoting
Da‐Long He, Xiao‐Yu Zhang, Jing‐Yang Su, Qi Zhang, Ling‐Xiao Zhao, Ting‐Yao Wu, Hang Ren, Rong‐Jun Jia, Xian‐Fang Lei, Wen‐Jia Hou, Wen‐Ge Sun, Yong‐Gang Fan, Zhan‐You Wang   +12 more
wiley   +1 more source

Supplementary Figures 1-2, Methods from Novel Matrix Metalloproteinase Inhibitor [¹⁸F]Marimastat-Aryltrifluoroborate as a Probe for <i>In vivo</i> Positron Emission Tomography Imaging in Cancer

, 2023
Ulrich auf dem Keller, Caroline L. Bellac, Ying Li, Yuanmei Lou, Philipp F. Lange, Richard Ting, Curtis Harwig, Reinhild Kappelhoff, Shoukat Dedhar, Michael J. Adam, Thomas J. Ruth, François Bénard, David M. Perrin, Christopher M. Overall   +13 more
openalex   +3 more sources

Prion Protein Endoproteolysis: Cleavage Sites, Mechanisms and Connections to Prion Disease

Journal of Neurochemistry, Volume 169, Issue 1, January 2025.
Endoproteolytic cleavage events affect the ability of the cellular prion protein (PrPC) to serve as a substrate for template‐mediated conversion into a misfolded isoform denoted PrPSc, a process integral to the pathogenesis of the fatal neurodegenerative disorders either known as transmissible spongiform encephalopathies or as prion diseases.
Andrew R. Castle, David Westaway
wiley   +1 more source

p53 modeling as a route to mesothelioma patients stratification and novel therapeutic identification

Journal of Translational Medicine, 2018
Background Malignant pleural mesothelioma (MPM) is an orphan disease that is difficult to treat using traditional chemotherapy, an approach which has been effective in other types of cancer.
Kun Tian, Emyr Bakker, Michelle Hussain, Alice Guazzelli, Hasen Alhebshi, Parisa Meysami, Constantinos Demonacos, Jean-Marc Schwartz, Luciano Mutti, Marija Krstic-Demonacos   +9 more
doaj   +1 more source

Strategies to improve platelet cryopreservation: A narrative review

Transfusion, Volume 65, Issue 4, Page 740-749, April 2025.
Lauren Waters, Denese C. Marks, Lacey Johnson   +2 more
wiley   +1 more source

Abstracts

Molecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Intraosseous infusion of the distal phalanx compared to systemic intravenous infusion for marimastat delivery to equine lamellar tissue.

The Veterinary Journal, 2015
C. Underwood, S. N. Collins, A. V. van Eps, P. C. Mills, R. Allavena, S. Bailey, C. M. Medina Torres, A. Meizler, C. Pollitt   +8 more
semanticscholar   +1 more source

Staphylococcus aureus toxins mediate endothelial Thrombomodulin release during severe invasive infections. [PDF]

Virulence
Seidner L, Tanaka E, Engstrand O, Nilsson S, Bergonzini A, Kaland L, Novello M, Svensson M, Norrby-Teglund A, Palma Medina LM.   +9 more
europepmc   +1 more source

Tanshinone IIA affects the proliferation of A549/Tax by affecting the expression of MMP7 through the PI3K-AKT-mTOR signaling pathway. [PDF]

Discov Oncol
Chen F, Xiang W, Qiang G.
europepmc   +1 more source