Results 71 to 80 of about 39,615 (215)

Natural Bioactive Cyclopeptides from Microbes as Promising Anticancer Drug Leads: A Mini-review

Indonesian Journal of Pharmacy, 2021
Natural products from microbes are a rich source of bioactive molecules to serve as drug leads, predominantly in cancer therapy. Peptides are among the essential nature-derived biomolecules.
Linda Sukmarini
doaj   +1 more source

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

Food Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso, A. M. Abd El‐Aty, Kwaku Amoah, Xianghong Ju   +3 more
wiley   +1 more source

Investigation of Marine-Derived Fungal Diversity and Their Exploitable Biological Activities

Marine Drugs, 2015
Marine fungi are potential producers of bioactive compounds that may have pharmacological and medicinal applications. Fungi were cultured from marine brown algae and identified using multiple target genes to confirm phylogenetic placement.
Joo-Hyun Hong, Seokyoon Jang, Young Mok Heo, Mihee Min, Hwanhwi Lee, Young Min Lee, Hanbyul Lee, Jae-Jin Kim   +7 more
doaj   +1 more source

Antarctic soil microbiomes encode structurally conserved and phylogenetically diverse beta‐lactamases

iMetaOmics, EarlyView.
An integrative metagenomic framework combining sequence, structural, and functional inference reveals a phylogenetically diverse and structurally conserved repertoire of putative beta‐lactamases across Antarctic soil microbiomes, with predominance of class A and subclass B3 enzymes and limited but detectable associations with mobile genetic elements ...
José Coche‐Miranda, Patricio Arros, Nicolás Canales, Camilo Berríos‐Pastén, Gastón Azziz, Rosalba Lagos, Julieta Orlando, Francisco P. Chávez, Andrés E. Marcoleta   +8 more
wiley   +1 more source

Diversity, Ecological Role and Biotechnological Potential of Antarctic Marine Fungi

, 2021
The Antarctic Ocean is one of the most remote and inaccessible environments on our planet and hosts potentially high biodiversity, being largely unexplored and undescribed.
Stefano Varrella, Cinzia Corinaldesi, Eugenio Rastelli, Antonio Dell’Anno, Giulio Barone, Michael Tangherlini   +5 more
core   +1 more source

Marine Peptides and Their Anti-Infective Activities

Marine Drugs, 2015
Marine bioresources are a valuable source of bioactive compounds with industrial and nutraceutical potential. Numerous clinical trials evaluating novel chemotherapeutic agents derived from marine sources have revealed novel mechanisms of action. Recently,
Hee Kyoung Kang, Chang Ho Seo, Yoonkyung Park   +2 more
doaj   +1 more source

Surfactant Enhanced Bioremediation of Saline Diesel Contaminated Water by a Novel Bacterial Halophilic Consortium

Journal of Surfactants and Detergents, EarlyView.
ABSTRACT The use of microorganisms is an evolving method for the degradation of hydrocarbon contaminants. In this aim, halophilic hydrocarbon degrading bacteria were isolated from oil contaminated soil in Tunisia. A lipopeptide biosurfactant produced by Bacillus subtilis SPB1 was tested to increase diesel biodegradation along with co‐inoculation with ...
Inès Mnif, Dhouha Ghribi
wiley   +1 more source

Optimizing germination and cultivation of edible halophytes using effluents from an IMTA system

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Halophytes offer nature‐based solutions to food insecurity and soil degradation, while their integration into integrated multi‐trophic aquaculture (IMTA) systems promotes circular economy practices. This study aimed to optimize the germination and cultivation of edible halophytic species, namely Limbarda crithmoides, Suaeda vera and
Viana Castañeda‐Loaiza, Maria João Rodrigues, Nuno Neng, Célia Quintas, Isabel Ratão, Luísa Custódio   +5 more
wiley   +1 more source

Penapisan Kapang Laut Penghasil Senyawa Sitotoksik dari Beberapa Perairan di Indonesia

Jurnal Pascapanen dan Bioteknologi Kelautan dan Perikanan, 2011
Marine-derived fungi have proven to be a rich source of cytotoxic compounds for the development of new anti cancer drugs. The aims of this research were to: 1) screen cytotoxic activity of marine fungi from Indonesian waters, 2) indentify marine fungus ...
Muhammad Nursid, Ekowati Chasanah, Murwantoko Murwantoko, Subagus Wahyuono   +3 more
doaj   +1 more source

Transcriptomic stress responses in Vaccinium spp. F1 hybrids: Implications for temperature‐resilient cranberry breeding using a crop wild relative

PLANTS, PEOPLE, PLANET, EarlyView.
Climate extremes threaten the sustainability of cranberry production, a culturally and economically important North American crop. This study demonstrates that wild cranberries (Vaccinium oxycoccos) harbor genetic variation that may enhance cold stress resilience when introduced into cultivated cranberry through hybridization.
Audrey Dickinson, Jackson Kubal, Nicholas Allsing, Emily Murray, Todd P. Michael, James J. Polashock   +5 more
wiley   +1 more source