Results 81 to 90 of about 548 (168)

Integrating infection intensity and aggregation into the dynamics of pathogens with within‐host replication

Journal of Animal Ecology, EarlyView.
We bridge micro‐ and macroparasite theory with a model tracking pathogen load heterogeneity. By incorporating load‐dependent mortality and within‐host pathogen growth, we show how pathogen load aggregation alters disease prevalence, host suppression effects, and virulence evolution, providing insights for managing complex infectious disease like ...
Ruijiao Sun, Jason Cosens Walsman, Mark Wilber, Cheryl J. Briggs   +3 more
wiley   +1 more source

Mechanistic insights into HapC: A key enzyme in prodiginine biosynthesis in Hahella chejuensis

The FEBS Journal, EarlyView.
HapC catalyzes prodiginine biosynthesis through coordinated movements of its ATP‐binding, substrate‐binding, and catalytic‐swivel domains. The enzyme shows tolerance toward short‐chain MAP analogs, and docking analyses reveal key residues and structural features underlying its substrate flexibility.
Yueh‐Te Chan, Aden Dhana Rizkita, Hsin‐Ju Hsieh, Shu‐Fang Hsu, Tony Eight Lin, Wei‐Jan Huang, Kai‐Cheng Hsu, Sheila Nathan, Peiching Chang, Andrew H.‐J. Wang, Cheng‐Chung Lee   +10 more
wiley   +1 more source

Structural and mutational analysis of Methanosarcina mazei prenylated FMN synthase reveals the basis of its unique prenyl donor substrate specificity

The FEBS Journal, EarlyView.
Some prenylated flavin mononucleotide (prFMN) synthases exceptionally prefer dimethylallyl phosphate (DMAP) over dimethylallyl diphosphate (DMAPP), which is a common prenyl donor substrate for many prenyltransferases. Structural and mutagenic analyses of Methanosarcina mazei prFMN synthase, which prefers DMAP but can also accept DMAPP, elucidated its ...
Sou Fukuhara, Hideaki Unno, Soma Ishimine, Ryuhei Nagata, Tomokazu Ito, Hisashi Hemmi   +5 more
wiley   +1 more source

De novo transcriptome assembly: a new laccase multigene family from the marine-derived basidiomycete Peniophora sp. CBMAI 1063

AMB Express, 2017
Laccases are multicopper oxidases that are able to catalyze reactions involving a range of substrates, including phenols and amines, and this ability is related to the existence of different laccases.
Igor Vinicius Ramos Otero, Milene Ferro, Maurício Bacci, Henrique Ferreira, Lara Durães Sette   +4 more
doaj   +1 more source

Fly me to the canopy: Diptera communities in oak forest crowns as bioindicators of stand decline

Insect Conservation and Diversity, EarlyView.
Diptera diversity: Oak decline increases the overall Diptera diversity, particularly in saproxylic and floricolous guilds, likely due to more open canopies and greater deadwood and floral resource availability. Family responses: Dolichopodidae, Empididae, Hybotidae and Anthomyiidae thrive in declining stands, whereas Mycetophilidae and other fungus ...
Anastasia Paupe, Elodie Le Souchu, Christophe Bouget, Christophe Daugeron, Clovis Quindroit, Pierre‐Yves Gloaguen, Patrick Grootaert, Mike Ashworth, Paul L. T. Beuk, Christophe Lauriaut, Valery O. Korneyev, Elena P. Kameneva, André Reimann, Julia J. Mlynarek, Jocelyn Claude, Pierre Tillier, Vivian Feng, Dalton de Souza Amorim, Rudolf Meier, Ximo Mengual, Tatiana Kúdelová, Thomas Lebard, Anders Lindström, Tobias Lilja, Santiago Jaume‐Schinkel, Jonas Mortelmans, Marija Ivković, David Brice, Bruno Righetti, Jean‐Paul Haenni, Pauline Bierre, Cécile Vincent‐Barbaroux, Aurélien Sallé   +32 more
wiley   +1 more source

Recent advances in the structures and bioactivities of benzopyrans derived from marine fungi: a review

Frontiers in Pharmacology
Marine fungi represent a treasure trove of bioactive secondary metabolites, with benzopyran compounds emerging as a significant class of these natural products.
Yidan Xi, Yidan Xi, Huannan Wang, Lixiang Sun, Xueyang Ma, Shuncun Zhang, Zhen Zhang   +6 more
doaj   +1 more source

Enhancing fish community monitoring at a cabled observatory by combining environmental DNA and imaging analysis

Journal of Fish Biology, EarlyView.
Abstract Cabled multiparametric observatories are sustaining ecological monitoring by collecting long‐term real‐time biological and environmental data. Here, we investigated fish communities by sampling environmental DNA (eDNA) over 4 days near the multiparametric cabled video‐observatory OBSEA (Northwestern Mediterranean Sea).
Maddalena Tibone, Marco Francescangeli, Sergio Stefanni, Jacopo Aguzzi, Bernadette O'Neill, Joaquin Del Rio, Daniel Mihai Toma, Luca Mirimin   +7 more
wiley   +1 more source

Cytotoxic Compounds from Marine Fungi: Sources, Structures, and Bioactivity

Marine Drugs
Marine fungi, such as species from the Penicillium and Aspergillus genera, are prolific producers of a diversity of natural products with cytotoxic properties.
Yukang Gao, Jianjian Wang, Pornphimon Meesakul, Jiamin Zhou, Jinyan Liu, Shuo Liu, Cong Wang, Shugeng Cao   +7 more
doaj   +1 more source

Dietary modulation of antimicrobial peptides (HAMP and LEAP2) in Chinook salmon (Oncorhynchus tshawytscha) fed a phytobiotic functional diet: Integrated genomic characterisation and tissue‐specific expression

Journal of Fish Biology, EarlyView.
Abstract Antimicrobial peptides (AMPs) are key components of the innate immune system in fish, providing rapid protection against microbial pathogens. Among these, the liver‐expressed antimicrobial peptides (LEAPs), comprising LEAP‐1 (hepcidin; HAMP) and LEAP‐2, play central roles in host defence and iron regulation.
Roberta Marcoli, Jane E. Symonds, Seumas P. Walker, Cesar Lopez, Mark A. Preece, Christopher Battershill, Steve Bird   +6 more
wiley   +1 more source

Screening Activities of Crude Extracts Produced Halodule sp. Seagrass-Associated Fungus

Ilmu Kelautan
Secondary metabolites from marine microorganisms, including marine-derived fungi, have consented to developing guide bioactive compounds. Marine-derived fungi were reported to be associated with various habitats, including seagrasses.
Safwan Safwan, Sucilawaty Ridwan, Musyarrafah Musyarrafah, Rina Wijayanti   +3 more
doaj   +1 more source